Curriculum Vitae

DR. ADYANI AZIZAH BINTI ABD HALIM

Senior Lecturer
  • Department of Oral and Craniofacial Sciences
    Faculty of Dentistry
  • adyaniazizah
  • 0379677405
  • 0196742377

AREAS OF EXPERTISE

  • CHEMICAL MODIFICATION
    Life Sciences, Biological Sciences, Biochemistry
  • OTHER BIOCHEMISTRY N.E.C
    Life Sciences, Biological Sciences, Biochemistry

ACADEMIC QUALIFICATION

  • PHD(UM), (Science)
    Universiti Malaya (UM)
  • MS(UM), (Science)
    Universiti Malaya (UM)
  • BSC(SAINS)(UM), (Science)
    Universiti Malaya (UM)

ADMINISTRATIVE DUTIES

  • Coordinator
    27 Feb 2025 - 26 Feb 2027 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Coordinator
    22 Oct 2025 - 08 Mar 2026 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Head of Department
    01 Apr 2023 - 19 Jan 2025 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Committee Members
    11 Dec 2025 - 30 Dec 2025 (Faculty)
  • Committee Members
    03 Nov 2025 - 11 Nov 2025 (Faculty)
  • Committee Members
    22 Oct 2025 - 29 Oct 2025 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Committee Members
    10 Jun 2024 - 09 Jun 2025 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Committee Members
    14 Apr 2025 - 21 May 2025 (Faculty)
  • Committee Members
    19 Jan 2022 - 18 Jan 2025 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Committee Members
    14 Feb 2024 - 14 Feb 2024 (University Malaya)
  • Acting Head of Department
    15 Aug 2022 - 31 Dec 2022 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Coordinator
    14 Dec 2021 - 18 Sep 2022 (Faculty)

MEMBERSHIPS

  • FULL MEMBER OF THE ROYAL SOCIETY OF BIOLOGY, MEMBER
    2025 to 2026 (International)
  • MEMBER OF MALAYSIAN SOCIETY OF ORAL MICROBIOLOGISTS AND ORAL IMMUNOLOGISTS, MEMBER
    Since 2018 (National)
  • FULL MEMBER OF ROYAL SOCIETY OF BIOLOGY (RSB), MEMBER
    2024 to 2025 (International)

AWARD AND STEWARDSHIP

  • Excellence Service Award
    2023, Universiti Malaya
  • Certificate of Excellent Service
    2021, Universiti Malaya

PUBLICATIONS

Article in Journal
WoS
  1. Abubakar, Mujaheed; Hidayat, Ahmad Fadhlurrahman Ahmad; Abd Halim, Adyani Azizah; Khanna, Kushagra; Zaroog, Mohammed Suleiman; Rajagopal, Mogana Sundari; Tayyab, Saad (2025). Assessing the molecular interaction between a COVID-19 drug, nirmatrelvir, and human serum albumin: calorimetric, spectroscopic, and microscopic investigations, ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES. . doi:10.1515/znc-2024-0223
  2. Abubakar, Mujaheed; Hidayat, Ahmad Fadhlurrahman Ahmad; Mohamad, Saharuddin Bin; Halim, Adyani Azizah Abd; Khanna, Kushagra; Rajagopal, Mogana S.; Tayyab, Saad (2025). Multifaceted analysis of bempedoic acid binding to subdomain IIA of human serum albumin, JOURNAL OF MOLECULAR STRUCTURE. 1322. doi:10.1016/j.molstruc.2024.140435
  3. Abubakar, Mujaheed; Mohamad, Saharuddin B.; Abd Halim, Adyani Azizah; Tayyab, Saad (2025). Unveiling the molecular interaction of hepatitis B virus inhibitor, entecavir with human serum albumin through computational, microscopic and spectroscopic approaches, JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. . doi:10.1080/07391102.2024.2311331
  4. Bakri, Husna Hazirah; Rahman, Syarifah Nur Syed Abdul; Abd Halim, Adyani Azizah; Baharuddin, Nor Adinar; Khan, Hasnah Begum Said Gulam; Abidin, Zamirah Zainal; Arzmi, Mohd Hafiz; Munadziroh, Elly; Harun, Wan Himratul Aznita Wan (2025). In vitro study of probiotic Lactobacillus helveticus: Antibacterial effects on Porphyromonas gingivalis, PLOS ONE. 20(8). doi:10.1371/journal.pone.0329497
  5. Fauzi, Muhammad Syazwan Ahmad; Sabri, Muhammad Syafiq Ahmad; Halim, Adyani Azizah Abd; Abidin, Siti Amalina Inche Zainal (2025). Combinatorial effects of hydroxyapatite and Tualang honey on medication-related osteonecrosis of the jaw (MRONJ): An in vitro study, JOURNAL OF STOMATOLOGY ORAL AND MAXILLOFACIAL SURGERY. 126(1). doi:10.1016/j.jormas.2024.101999
  6. Hidayat, Ahmad Fadhlurrahman Ahmad; Mohamad, Saharuddin B.; Tayyab, Saad; Harun, Wan Himratul Aznita Wan; Abd Halim, Adyani Azizah (2025). Molecular interaction of a protease inhibitor, leupeptin, with human serum albumin: Insights from calorimetry, spectroscopy, microscopy, and computational approaches, JOURNAL OF MOLECULAR STRUCTURE. 1321. doi:10.1016/j.molstruc.2024.139670
  7. Mohd Asngari, Nurul Jannah; Rehman, Fazal; Bin Mohamad, Saharuddin; Tayyab, Saad; Bakar, Khairul Azreena; Feroz, Shevin Rizal; Syed Abdul Rahman, Syarifah Nur; Inche Zainal Abidin, Siti Amalina; Abdul Razak, Fathilah; Abd Halim, Adyani Azizah (2025). Binding interactions between ar-turmerone and human serum albumin: mechanistic and biophysical insights, JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. . doi:10.1080/07391102.2025.2543359
  8. Rehman, Fazal; Mohamad, Saharuddin B.; Abd Rahman, Siti Nor Aisyah; Othman, Muhamad Aqmal; Paterson, Ian C.; Halim, Adyani Azizah Abd; Sundari Rajagopal, Mogana; Tayyab, Saad (2025). Integrative analysis of the anti-diabetic inhibitor GW9508 binding to human serum albumin: computational, spectroscopic and ITC insights, JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. . doi:10.1080/07391102.2025.2531181
  9. Asngari, Nurul Jannah Mohd; Bakar, Khairul Azreena; Feroz, Shevin Rizal; Razak, Fathilah Abdul; Abd Halim, Adyani Azizah (2024). Interaction mechanism of a cysteine protease inhibitor, odanacatib, with human serum albumin: In vitro and bioinformatics studies, BIOPHYSICAL CHEMISTRY. 305. doi:10.1016/j.bpc.2023.107140
  10. Rehman, Fazal; Abubakar, Mujaheed; Ridzwan, Nor Farrah Wahidah; Mohamad, Saharuddin B.; Abd. Halim, Adyani Azizah; Tayyab, Saad (2024). Deciphering the binding mode and structural perturbations in floxuridine-human serum albumin complexation with spectroscopic, microscopic, and computational techniques, SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY. 308. doi:10.1016/j.saa.2023.123641
  11. Abubakar, Mujaheed; Mohamed, Saharuddin B.; Halim, Adyani Azizah Abd; Tayyab, Saad (2023). Use of computational and wet lab techniques to examine the molecular association between a potent hepatitis C virus inhibitor, PSI-6206 and human serum albumin, SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY. 294. doi:10.1016/j.saa.2023.122543
  12. Hasnan, M. M. I. Megat; Lim, G. P.; Nayan, N.; Soon, C. F.; Abd Halim, A. A.; Ahmad, M. K.; Said, S. M.; Ali, M. S. Mohamed; Noor, I. M. (2023). The investigation of chlorpyrifos (Cpy) detection of PEDOT:PSS-MXene(Ti2CTX)-BSA-GO composite using P-ISFET reduction method, POLYMER BULLETIN. . doi:10.1007/s00289-022-04105-5
  13. Tayyab, Saad; Tio, Jaclyn Wei Qi; Abd Halim, Adyani Azizah (2023). THE FLUORESCENCE SIGNAL OF ALBUMIN-BOUND BILIRUBIN TO MONITOR DRUG-INDUCED BILIRUBIN DISPLACEMENT FROM HUMAN SERUM ALBUMIN, REVUE ROUMAINE DE CHIMIE. 68(9), 429-434. doi:10.33224/rrch.2023.68.9.03
  14. Abubakar, Mujaheed; Kandandapani, Salanee; Mohamed, Saharuddin B.; Abd Halim, Adyani Azizah; Tayyab, Saad (2022). Shedding light on the molecular interaction between the Hepatitis B virus inhibitor, clevudine, and human serum albumin: Thermodynamic, spectroscopic, microscopic, and in silico analyses, JOURNAL OF MOLECULAR LIQUIDS. 368. doi:10.1016/j.molliq.2022.120737
  15. Tayyab, S.; Mat, T. N. N. Tuan; Abd Halim, A. A. (2022). DIFFERENTIAL STABILIZING EFFECTS OF BUFFERS ON STRUCTURAL STABILITY OF BOVINE SERUM ALBUMIN AGAINST UREA DENATURATION, LATIN AMERICAN APPLIED RESEARCH. 52(1), 7-13. doi:10.52292/j.laar.2022.738
  16. Tan, C. Y., Lim, C. S., Liew, S. M., Abd Halim, A. A., & Tayyab, S. (2021). Lysine modification of human serum albumin and its effect on protein conformation and nalidixic acid binding. Journal of the Indian Chemical Society, 98(3). doi: 10.1016/j.jics.2021.100031
  17. Rizwan, M., Yahya, R., Hassan, A., Yar, M., Abd Halim, A. A., Al-Maleki, A. R., . . . Zubairi, W. (2019). Novel chitosan derivative based composite scaffolds with enhanced angiogenesis; potential candidates for healing chronic non-healing wounds. Journal of Materials Science-Materials in Medicine, 30(6), 11. doi:10.1007/s10856-019-6273-3
  18. Saufi, Aimi Nabila Mohamad; Ridzwan, Nor Farrah Wahidah; Bin Mohamad, Saharuddin; Tayyab, Saad; Abd Halim, Adyani Azizah (2019). Fluorometric and Docking Analysis of the Complex Formation between an Anti-cancer Drug, Chlorambucil and Bovine Serum Albumin, INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH. 53(4), 682-687. doi:10.5530/ijper.53.4.131
  19. Abd Halim, A. A., Kadir, H. A., Tayyab, S. (2017). INCREASED CHEMICAL STABILITY OF BACILLUS LICHENIFORMIS alpha-AMYLASE UPON ACETYLATION. Studia Universitatis Babes-Bolyai Chemia, 62(2), 319-332. doi:10.24193/subbchem.2017.2.25
  20. Abd Halim, A. A., Zaroog, M. S., Kadir, H. A., Tayyab, S. (2017). Alcohol-induced structural transitions in the acid-denatured Bacillus licheniformis alpha-amylase. Journal of Saudi Chemical Society, 21, S349-S358.
Scopus
  1. Halim A.A.A., Ridzwan F.W., Mohamad S.B., Tayyab S. (2022). Targeting the nalidixic acid binding site on human serum albumin through computational approach: A re-investigation, Biointerface Research in Applied Chemistry. 12(2), 1520-1525. doi:10.33263/BRIAC122.15201525
  2. Tayyab S., Mat T.N.N.T., Halim A.A.A. (2022). DIFFERENTIAL STABILIZING EFFECTS OF BUFFERS ON STRUCTURAL STABILITY OF BOVINE SERUM ALBUMIN AGAINST UREA DENATURATION, Latin American Applied Research. 52(1), 7-13. doi:10.52292/j.laar.2022.738
Others
  1. Fathilah A. Razak, Syarifah Nur S.A. Rahman, Nur Sariyah M. Rosli, Azrin A.A. Rahim, Adyani A.A. Halim and Muhammad Luthfi, 2021. Natural sweetness of fruits may lead to cariogenic oral biofilm: An in vitro study. Pak. J. Nutr., 20: 101-107.

RESEARCH INTEREST

  • Protein stability, Protein folding and unfolding, Protein denturation, Ligand-protein interaction (Protein stability, Protein denturation, Ligand-protein interaction, albumin)

RESEARCH PROJECT

National
  1. 2020 - 2025, Fundamental Research Grant Scheme (FRGS)
    Evaluation Of The Properties Of Lactobacillus Helveticus On The Fimbriae Genes Of Porphyromonas Gingivalis In Subgingival Biofilm Associated With Periodontitis ( Co-Researcher)
  2. 2020 - 2024, Fundamental Research Grant Scheme (FRGS)
    Characterisation On The Interaction Of Potential Gingipain Inhibitor Drugs With Human Serum Albumin ( Principal Investigator(PI))
  3. 2018 - 2021, RU Geran - Fakulti Program
    Interaction Of Various Cystein Protease And Wnt/b-catenin Inhibitors With Human Serum Albumin: Spectroscopic And Molecular Modelling Approach ( Principal Investigator(PI))

PAPER PRESENTED

INVITED SPEAKER
  1. Experimental Laboratory, Guest Lecture, Faculty of Dentistry Universitas Sumatera Utara (International) (09 May 2025 - 09 May 2025)
  2. Application of Natural Resources in Dentistry, International Summer Course, Fakultas Kedokteran Gigi, Universitas Sumatera Utara (International) (03 Jul 2023 - 04 Jul 2023)
ORAL PRESENTER
  1. Exploring the interactions of ethyl 4-methoxycinnamate and human serum albumin, MI-PHARMCONFERENCE 2023, Faculty of Pharmacy and Biomedical Sciences (University) (06 Oct 2023 - 07 Oct 2023)
  2. Ungku Ismail, U.F.W., Yosri, A., Syed Abdul Rahman, S.N., & Halim, A.A.A. Effect of a therapeutic flavonoid on the morphology and growth of hydroxyapatite crystals , 12th National Dental Students Scientific Conference , NDSSC 2020  (National) (02 Nov 2020 - 02 Nov 2020)
POSTER PRESENTER
  1. Interactions Between Malabaricone-C and Human Serum Albumin, The 33rd Intervarsity Biochemistry Seminar, Fakulti Sains dan Teknologi (National) (09 Dec 2023 - 09 Dec 2023)
  2. Interactions Between Malabaricone-A and Human Serum Albumin, The 33rd Intervarsity Biochemistry Seminar, Fakulti Sains dan Teknologi (University) (09 Dec 2023 - 09 Dec 2023)
  3. Mohd Asngari, N.J., Abdul Razak, F., & Halim, A.A.A. Fluorescence study on the interaction of cysteine protease inhibitor, odanacatib with human serum albumin. , 3rd ICOMOI 2020 & 13th POSTGRADUATE CONFERENCE 2020, Malaysian Society of Oral Microbiology and Oral Immunology (International) (08 Sep 2020 - 09 Sep 2020)
  4. Differential Stabilizing Effects of Buffers on Structural Stability of Bovine Serum Albumin Against Urea Denaturation , 30th Intervarsity Biochemistry Seminar, University of Nottingham Malaysia (National) (04 May 2019 - 04 May 2019)

ACADEMIC/ PROF. SERVICES

Evaluation
  1. (2025) Binding Investigation of Ribociclib to Human α-1-acid Glycoprotein With Spectroscopic and Computational Simulation Approaches, International, (Reviewer)
  2. (2025) Doctoral Thesis Examination, University, (Internal Examiner)
  3. (2025) Structural and Thermal Impacts of Phosalone Binding to Human Serum Albumin: Perspectives from Molecular Modeling and Spectroscopic Methods, International, (Reviewer)
  4. (2025) Insights Into The Interaction Mechanism Between Chlordecone and Human Serum Albumin by Multi-spectroscopy and Molecular Docking, International, (Reviewer)
  5. (2024) Pengerusi Bagi Pembentangan Research Proposal Defense Pelajar Prostodontik Tahun 1 Sesi 2024/2025, University, (Reviewer)
  6. (2024) Proposal Defence-farhana Sikder, University, (Reviewer)
  7. (2024) Panel Pembentangan Research Proposal Defence: Dr. Jegadesbari Ganapathy, University, (Reviewer)
  8. (2024) Candidature Defense-anna Kang Chee Wong, University, (Internal Examiner)
  9. (2024) Proposal Defense-zarith Shafinaz Dol Bakri, University, (Reviewer)

SUPERVISION

Under Graduate Students
  1. (2022) Biocompatibility of hydroxyapatite-nanoparticle of Bosenbergia rotunda - NURUL ILLYANA BINTI MOHAMAD RISTAK
  2. (2022) Biocompatibility of hydroxyapatite-nanoparticle of Bosenbergia rotunda - MUHAMMAD AKMALHAKIM BIN AHMAD KAMIL
  3. (2022) BIOACTIVITIES OF HYDROXYAPATITE COATED WITH TUALANG HONEY ON MEDICATION-RELATED OSTEONECROSIS OF THE JAW (MRONJ) - MUHAMMAD SYAZWAN BIN AHMAD FAUZI
  4. (2022) BIOACTIVITIES OF HYDROXYAPATITE COATED WITH TUALANG HONEY ON MEDICATION-RELATED OSTEONECROSIS OF THE JAW (MRONJ) - MUHAMMAD SYAFIQ BIN AHMAD SABRI
  5. (2021) Influence of various type of foods on the expression and activity of salivary alpha-amylase - Khairul Nabila Rashidi
  6. (2021) Influence of various type of foods on the expression and activity of salivary alpha-amylase - Abbas bin Harith
Postgraduate Student
PhD/ Doctoral
  1. (2025) Biophysical and Computational Approaches for Elucidating the Interaction Mechanisms of Selected Antidiabetic Drugs with Human Serum Albumin, FAZAL REHMAN
  2. (2025) Binding of Anti-Inflammatory Compounds to Human Serum Albumin: In Vitro and In Silico Insights, AHMAD FADHLURRAHMAN BIN AHMAD HIDAYAT
  3. (2024) Antiproliferative Effects of Curcuma Purpurascens on H103 and its Interaction Mechanism with Human Serum Albumin, NURUL JANNAH BINTI MOHD ASNGARI
  4. (2023) Targeting Mode of Binding Between Virus Inhibitors and Human Serum Albumin in Hepatitis B and C Through Spectroscopic and Molecular Modeling Approaches, MUJAHEED ABUBAKAR
Master
  1. (2025) CYTOTOXICITY AND ANTI MOTILITY OF BOESENBERGIA ROTUNDA DICLOROMETHANE EXTRACT LOADED PLGA NANOPARTICLES (BRDE-PLGA NPS) AGAINST HUMAN ORAL CANCER CELLS, TAN CHIN HOONG
  2. (2023) Exploring Molecular Recognition Between an Antineoplastic Drug, Floxuridine, and Human Serum Albumin Through Spectroscopic, Computational and Atomic Force Microscopic Approaches, FAZAL REHMAN
  3. (2019) Underlying mechanism of antitumor effects of Curcuma purpurascens extracts on oral squamous cell carcinoma (OSCC), NURUL JANNAH BINTI MOHD ASNGARI

TEACHING

Master
  1. (2024) DXGC6180 - Kursus Sains Asas Perubatan (bms) Sesi 2023/2024, Fakulti Pergigian
  2. (2023) DSA7003 - Kursus Asas Sains Perubatan (bms) Sesi 2022/2023, Fakulti Pergigian
  3. (2023) DXGC6180 - Kursus Sains Asas Perubatan (bms) Sesi 2022/2023, Fakulti Pergigian
Bachelor
  1. (2024) DIA1001 - Oral Biology
  2. (2022) - - Cased Based Learning
  3. (2022) DIA1001 - Oral Biology
  4. (2018) DIA1001 - Oral Biology

SOCIAL RESPONSIBILITY ACTIVITIES

  • Umhakcs 4.0 Volunteer, (12 Apr 2021 - 07 May 2021) (University)
  • Colon Cancer Awareness Virtual Run, (10 Dec 2020 - 31 Jan 2021)
  • Sumbangan Kemasyarakatan Untuk Projek Ramadhan Donation Drive 2019 Kepada Pelajar B40 Fakulti Pergigian, Universiti Malaya, (13 May 2019 - 31 May 2019)