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CURRICULUM VITAE
PERSONAL DETAIL

Name
  Prof. Dr. Ling Tau Chuan
Designation
  Professor
Department
  Institute of Biological Sciences
Faculty
  Faculty of Science
Tel. No. (Office)
  +60379674104
E-mail Address
  tcling@um.edu.my
ResearcherID Link
  http://www.researcherid.com/rid/F-5137-2011
Address(Office)
  Institute of Biological Sciences, Faculty of Science Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA

ACADEMIC QUALIFICATION
(Qualification), (Institution).
PhD(Chemical Engineering), BIRMINGHAM UNIVERSITY, BIRMINGHAM, UK
MSc(Environmental Engineering), UNIVERSITI PUTRA MALAYSIA (UPM)
BSc(Hons)(Biotechnology), UNIVERSITI PERTANIAN MALAYSIA

PROFESSIONAL AFFILIATION/MEMBERSHIP
(Organisation), (Role), (Year), (Level).

Current Biochemical Engineering Journal, Editorial Board Member, 2013, (International)

The Institution of Chemical Engineer (IChemE), Member, 2013, (International)

The Open Biotechnology Journal , Editorial Board Member, 2013, (International)

CHARTERED ENGINEER OF ENGINEERING COUNCIL, UNITED KINGDOM (CENG), Charted Engineer, 2011, (International)

American Chemical Society, Member, 2010, (International)

Federation of European Biotechnology, Member, 2009, (International)

Malaysia Society of Molecular Biology and Biotechnology, Member, 2009, (National)

ADMINISTRATIVE DUTIES
(Role), (Level), (Start date),(End Date).


Jawatan Kuasa Ijazah Tinggi (Fakulti), Institute Of Biological Sciences, Faculty Of Science, 23-Jul-13

Coordinator for Master of Biotechnology, Institute Of Biological Sciences, Faculty Of Science, 01-Jul-12 - 30-Jun-13

CAREER HISTORY
(Post), (Organisation), (Period).


Visiting Scholar , Lund University, Sweden ( Eramus Mundus Scholarship program), 18/09/2013

Visiting Professor, College of Chemistry and Chemical Engineering, Xiamen University, China, 13/08/2011 until 27/08/2011

Visiting Professor, College of Engineering, Yuan Ze University, Taiwan , 20/11/2007 until 20/12/2007

AREAS OF EXPERTISE
(Area).

Downstream Processing (Bioseparation, Product Recovery, Adsorbent Design and Fabrication)

Bioprocess Engineering (Bioproducts and Food Processing)

RECENT SELECTED PUBLICATIONS
(Publication).
 
Article In Academic Journals
 
2014

Saat, M.N., Annuar, M.S.M., Alias, Z., Ling, T. C. and Chisti, Y. (2014) Modeling of growth and laccase production by Pycnoporus sanguineus, Bioprocess and Biosystems Engineering, 37, 765 - 775. (ISI-Cited Publication)

Abbasiliasi,S., Tan,J.S., Tengku Ibrahim,T.A., Kadkhodaei, S., Ng,H.S., Vakhshiteh,F., Ajdari,Z., Mustafa,S., Ling, T. C., Abdul Rahim,R., Ariff,A. (2014) Primary recovery of a bacteriocin-like inhibitory substance derived from Pediococcus acidilactici Kp10 by an aqueous two-phase system, Food Chemistry, 151, 93 - 100. (ISI-Cited Publication)

Rosti,I.A., Ramanan, R.N., Tan,J.S., Ling, T. C., Ariff,A. (2014) Recovery of microquantities of human epidermalgrowth factor from Escherichia coli homogenate and pichia pastoris culture medium using expanded bed adsorption, Separation Science and Technology, 49, 702 - 708. (ISI-Cited Publication)

Ali,S.M., Ling, T. C., Muniandy,S., Tan,Y.S., Raman,J., Sabaratnam,V. (2014)Recovery and partial purification of fibrinolytic enzymes of Auricularia polytricha (Mont.) Sacc by an aqueous two-phase system, Separation and Purification Technology, 122, 359 - 366. (ISI-Cited Publication)

Ng, S.P.,Lai,O.M.,Abas, F., Lim, H.K., Beh, B.K.,Ling, T. C., Tan., C.P.(2014)Compositional and thermal characteristics of palm olein-based diacylglycerol in blends with palm super olein, Food Research International, 55,62 - 69. (ISI-Cited Publication)

Tang,M.S.Y., Show,P.S., Lin,Y.K., Woon,K.L., Tan,C.P., Ling, T. C. (2014)Separation of single- walled carbon nanotubes using aqueous two-phase system, Separation and Purification Technology, 125, 136 - 141. (ISI-Cited Publication)

Leong, Y.K., Show, P.L., Ooi, C.W., Ling, T. C., Lan, J.C.W. (2014) Current trends in polyhydroxyalkanoates (PHAs) biosynthesis: Insights from the recombinant Escherichia coli, Journal of Biotechnology, 180, 52 - 65. (ISI-Cited Publication)

Anarjan, N., Jafarizadeh Malmiri, H., Ling, T. C., Tan, C.P.(2014) Effects of pH, ions, and thermal treatments on physical stability of astaxanthin nanodispersions, International Journal of Food Properties, 17, 937 - 947. (ISI-Cited Publication)

Noor, S.S.M., Tey, B.T., Tan, W.S., Ling, T. C., Ramanan, R.N., Ooi, C.W. (2014) Purification of recombinant green fluorescent protein from escherichia coli using hydrophobic interaction chromatography, Journal of Liquid Chromatography and Related Technologies, 37, 1873 - 1884. (ISI-Cited Publication)
 
2013

Ng,E.P., Goh,J.Y., Ling,T. C., Mukti,R.R.(2013) Eco- friendly synthesis for MCM-41 nanoporous materials using the non-reacted reagents in mother liquor, Nanoscale Research Letters,8,120 (ISI-Cited Publication)

Chan, S.W., Mirhosseini, H., Taip, F.S., Ling, T. C., Tan, C.P., (2013),Stability of CoQ10-loaded oil-in- water (O/W) emulsion: Effect of carrier oil and emulsifier type, Food Biophysics, 8, 273 - 281. (ISI-Cited Publication)

Ng, H.S., Ooi, C.W., Mokhtar, M.N., Show,P.L. Ariff,A., Tan,J.S., Ng,E.P., Ling, T. C.(2013) Extractive bioconversion of cyclodextrins by Bacillus cereus cyclodextrin glycosyltransferase in aqueous two- phase system, Bioresource Technology, 142, 723 - 726. (ISI-Cited Publication)

Chan, S.W., Mirhosseini, H., Taip, F.S., Ling, T.C., Tan, C.P., (2013), Comparative study on the physicochemical properties of arrageenan extracted from Kappaphycus alvarezii (doty) doty ex Silva in Tawau, Sabah, Malaysia and commercial arrageenans, Food Hydrocolloids, 30, 581-588. (ISI-Cited Publication)

Sunantha,K., Soottawat,B., Ling, T. C., Oscar,M., Saroat, R. (2013)Enhanced recovery of alkaline protease from fish viscera by phase partitioning and its application, Chemistry Central Journal, 7, 79 - 86. (ISI-Cited Publication)

Chow,Y.H., Yap, Y.J., Anuar,M.S., Tejo,B.A., Ariff,A., Show,P.L., Ng,E.P., Ling, T. C. (2013) Interfacial partitioning behaviour of bovine serum albumin in polymer-salt aqueous two-phase system, Journal of Chromatography B, 934, 71 - 78. (ISI-Cited Publication)

Show, P.L.,Ooi, C.W., Anuar, M.S., Ariff,A., Yusof,Y.A., Chen, S.K., Mohamad Annuar,M.S., Ling,T. C. (2013) Recovery of lipase derived from Burkholderia cenocepacia ST8 using sustainable aqueous two-phase flotation composed of recycling hydrophilic organic solvent and inorganic salt, Separation and Purification Technology, 110, 112 - 118.. (ISI-Cited Publication)

Tan, J.S., Ling, T.C., Mustafa,S., Tam, Y.J., Ramanan,R.N., Ariff, A. (2013)An integrated bioreactor- expanded bed adsorption system for the removal of acetate to enhance the production of alpha-interferon- 2b by Escherichia coli, Process Biochemistry, 48, 551 - 558. (ISI-Cited Publication)

Lin, Y. K., Ooi, C.W., Tan, J.S., Show, P.L., Ariff, A., Ling, T. C. (2013) Recovery of human interferon alpha-2b from recombinant Escherichia coli using alcohol/salt-based aqueous two-phase system, Separation and Purification Technology, 120, 362 - 366. (ISI-Cited Publication)
 
2012

Show, P. L., Tan, C. P., Anuar, M. S., Ariff, A., Yusof, Y. A., Chen, S. K., Ling, T. C. (2012), Primary recovery of lipase derived from Burkholderia cenocepacia strain ST8 and recycling of phase components in an aqueous two-phase system, Biochemical Engineering Journal, 60, 74 - 80. (ISI-Cited Publication)

Selvakumar,P., Ling, T.C., Walker, S., Lyddiatt, A. (2012),Recovery of glyceraldehyde 3-phosphate dehydrogenase from an unclarified disrupted yeast using aqueous two-phase systems facilitated by distribution analysis of radiolabelled analytes, Separation and Purification Technology, 85,28 - 34. (ISI-Cited Publication)

Lin, Y. K., Ooi,C. W., Ramanan, R. N., Ariff, A., Ling, T. C. (2012)Recovery of human interferon alpha- 2b from recombinant Escherichia coli by aqueous two- phase system,Separation Science and Technology, 47, 1023 - 1030. (ISI-Cited Publication)

Ng, H. S., Tan, C. P., Mokhtar, M. N., Ibrahim, S., Ariff, A., Ooi, C. W., Ling, T. C. (2012), Recovery of Bacillus cereus cyclodextrin glycosyltransferase and recycling of phase components in an aqueous two-phase system using thermo-separating polymer, Separation and Purification Technology,89, 9 - 15. (ISI-Cited Publication)

Show, P. L., Tan, C. P., Anuar, M. S., Ariff, A., Yusof, Y. A., Chen, S. K., Ling, T. C. (2012),Extractive fermentation for improved production and recovery of lipase derived from Burkholderia cepacia using a thermoseparating polymer in aqueous two-phase systems, Bioresource Technology, 116, 226 - 233. (ISI-Cited Publication)

Zulkurnaina,M., Lai, O.M., Latip,R. A., Nehdie, I. A., Ling,T. C., Tan, C. P. (2012) The effects of physical refining on the formation of 3-monochloropropane-1,2- diol esters in relation to palm oil minor components, Food Chemistry, 135, 799-805. (ISI-Cited Publication)

Selvakumar, P., Ling, T. C., Walker, S., Lyddiatt, A. (2011), Partitioning of haemoglobin and bovine serum albumin from whole bovine blood using aqueous two- phase systems, Separation and Purification Technology, 90, 182 - 188. (ISI-Cited Publication)

Selvakumar, P., Ling, T. C., Covington, A. D., Lyddiatt, A. (2012),Enzymatic hydrolysis of bovine hide and recovery of collagen hydrolysate in aqueous two-phase systems, Separation and Purification Technology, 89,282 - 287. 282 - 287. (ISI-Cited Publication)

Anarjan, N., Tan, C.P., Nehdi, I.A., Ling, T. C. (2012) Colloidal astaxanthin: Preparation, characterization and bioavailability evaluation, Food Chemistry, 135, 1303-1309. (ISI-Cited Publication)

Abbasiliasi, S ., Tan, J.S., Ibrahim, T.A., Ramanan, R.N., Vakhshiteh, F., Mustafa, S., Ling, T.C., Rahim, R.A., Ariff, A. (2012), Isolation of pediococcus acidilactici Kp10 with ability to secrete bacteriocin- like inhibitory substance from milk products for applications in food industry, BMC Microbiology, 12, 260 265. (ISI-Cited Publication)
 
2011

Tan, J. S., Nagasundra, R. R., Ling, T. C., Mustafa, S., Ariff, A. (2011), Enhanced production of periplasmic interferon alpha-2b by Escherichia coli using ion-exchange resin for in situ removal of acetate in the culture, Biochemical Engineering Journal, 58, 124 - 132. (ISI-Cited Publication)

Lan, C. W. J., Ling, T. C., O'Sullivan, D., A Lyddiatt, A.(2011), Integrated fluidized bed affinity recovery of an anti-MUC1 mucin recombinant diabody from Escherichia coli lysates, Separation and Purification Technology, 83, 204-207. (ISI-Cited Publication)

Tan, J. S., Nagasundra, R. R., Ling, T. C., Mustafa, S., Ariff, A. (2011), The role of lac operon and lac repressor in the induction using lactose for the expression of periplasmic human interferon by Escherichia coli, Annals of Microbiology, In Press (ISI-Cited Publication)

Show, P. L., Tan, C. P., Anuar, M. S., Ariff, A., Yusof, Y. A., Chen, S. K., Ling, T. C. (2011), Direct recovery of lipase derived from Burkholderia Cepacia with aqueous two-phase flotation, Separation and Purification Technology, 80, 577 - 584. (ISI-Cited Publication)

Ooi, C. W., Tan, C. P., Hii, S. L., Ariff,A., Ibrahim, S., Ling, T. C.(2011), Primary recovery of lipase derived from Burkholderia sp. ST8 with aqueous micellar two-phase system, Process Biochemistry, 46, 1847 - 1852 (ISI-Cited Publication)

Ng, H.S., Tan, C.P., Chen, S.K., Mokhtar, M.N., Ariff, A., Ling, T.C. (2011), Primary capture of cyclodextrin glycosyltransferase derived from Bacillus cereus by aqueous two phase system, Separation and Purification Technology, 81, 318-324 (ISI-Cited Publication)

Anarjan, N., Tan, C. P., Ling, T. C., Lye, K. L., Malmiri, H. J., Nehdi, I., Cheah, Y. K., Mirhosseini, H., Baharin, B. S. (2011), Effect of organic phase solvents on physicochemical properties and cellular uptake of astaxanthin nanodispersions, Journal of Agricultural and Food Chemistry, 59, 8733 - 8741 (ISI-Cited Publication)

Amid, M., Tan, C. P., Mirhosseini, H., Norashikin, Ab. Aziz, Ling, T. C. (2011) Optimisation of serine protease extraction from mango peel (Mangifera Indica Cv. Chokanan), Food Chemistry, 124, 666 - 671. (ISI-Cited Publication)

Ooi, C. W., Hii, S. L., Mustapa Kamal, S. M., Ariff, A., Ling, T. C. (2011) Extractive fermentation using aqueous two-phase systems for integrated production and purification of extracellular lipase derived from Burkholderia pseudomallei, Process Biochemistry, 46, 68 73. (ISI-Cited Publication)

Rattana, W., Tey, B. T., Tan, W. S., Subramanian, S. K., Taip, F.S., Ling, T. C (2011), Purification of rabbit polyclonal immunoglobulin G using anion exchangers, Process Biochemistry, 46, 101 - 107. (ISI-Cited Publication)

Amid M., Tan C. P., Mirhosseini H., Norashikin Ab. Aziz, Ling, T. C. (2011) Optimisation of freeze drying conditions for purified serine protease from mango (Mangifera Indica Cv. Chokanan) peel, Food Chemistry, 128, 158 164. (ISI-Cited Publication)

Luechau, F., Ling, T. C., Lyddiatt, A. (2011), Selective partition of plasmid DNA and RNA from crude Escherichia coli cell lysate by aqueous two-phase systems, Biochemical Engineering Journal, 55, 230 - 232 (ISI-Cited Publication)

Luechau, F., Ling, T. C., Lyddiatt, A. (2011), Recovery of B19 particles using aqueous two-phase systems, Food and Bioproducts Processing, 89, 322-327. (ISI-Cited Publication)
 
2010

Tan J. S., Ramanan R. N. , Ling T. C., Shuhaimi M., Ariff A. B. (2010), Comparison of predictive capabilities of response surface methodology and artificial neural network for optimization of periplasmic interferon-a2b production by recombinant Escherichia coli, MINERVA BIOTECNOLOGICA, 22, 63 73. (ISI-Cited Publication)

Chong, F.C., Tan, W.S., Awang Biak, D.R., Ling, T.C., Tey, B.T. (2010) Modulation of protease activity to enhance the recovery of recombinant nucleocapsid protein of Nipah virus , Process Biochemistry, 45, 133 137. (ISI-Cited Publication)

Ramanan, R.M., Ling, T.C., Tey, B.T., Ariff, A. (2010) Optimization of osmotic shock process variables for enhancement of the release of periplasmic interferon- from Escherichia coli using response surface method, Process Biochemistry, 45, 196 202. (ISI-Cited Publication)

Chong, F.C., Tan, W.S., Awang Biak, D.R., Ling, T.C., Tey, B.T. (2010) A preparative hydrophobic interaction chromatography for purification of recombinant nucleocapsid protein of Nipah virus from clarified Escherichia coli homogenate, Separation and Purification Technology, 71, 97 101. (ISI-Cited Publication)

Chong, F.C., Tan, W.S., Awang Biak, D.R., Ling, T.C., Tey, B.T. (2010), Direct recovery of recombinant nucleocapsid protein of Nipah virus from unclarified Escherichia coli homogenate using hydrophobic interaction expanded bed adsorption chromatography, Journal of Chromatography A, 1217, 1293 1297. (ISI-Cited Publication)

Luechau, F., Ling, T.C., Lyddiatt, A. (2010), Physical characterisations of a single-stage K hni-type aqueous two-phase extraction column, Biochemical Engineering Journal, 50, 90 98. (ISI-Cited Publication)

Luechau, F., Ling, T.C., Lyddiatt, A. (2010), A descriptive model and methods for up-scaled process routes for interfacial partition of bioparticles in aqueous two-phase systems, Biochemical Engineering Journal , 50, 122 130. (ISI-Cited Publication)

Selvakumar,P., Ling, T.C., Walker, S., Lyddiatt, A. (2010), Redefinition of working aqueous two phase systems:A generic description for prediction of the effective phase chemical composition for process control and biorecovery, Journal of Chromatography B, 878, 1784 1790. (ISI-Cited Publication)

Luechau, F., Ling, T.C., Lyddiatt, A. (2010), Two-step process for initial capture of plasmid DNA and partial removal of RNA using aqueous two-phase systems, Process Biochemistry, 45, 1432 1436. (ISI-Cited Publication)

Selvakumar,P., Ling, T.C., Walker, S., Lyddiatt, A. (2010), A Practical implementation and exploitation of ATPS for intensive processing of biological feedstock: A novel approach for heavily biological feedstock loaded ATPS, Separation and Purification Technology,75, 323 331. (ISI-Cited Publication)

Chew, F.N., Tan, W.S., Ling, T.C., Tey, B.T. (2011) Optimization of a native electrophoretic process for the purification of the intracellular green fluorescent protein from intact Eschericia coli cells, Process Biochemistry, 46, 399 403. (ISI-Cited Publication)
 
2009

Ho, C.W., Tan, W.S., Kamaruddin, S., Ling, T.C., Tey, B.T. (2009) A preparative purification process for recombinant hepatitis B core antigen using on-line capture by expanded bed adsorption followed by size exclusion chromatography. Journal of Microbiology and Biotechnology, 19, 416 423. (ISI-Cited Publication)

Chew, F.N., Tan, W.S., Ling, T.C., Tan, C.S., Tey, B.T. (2009) Quatitation of green fluorescent protein using a gel based imaging method, Analytical Biochemistry, 384, 353 355. (ISI-Cited Publication)

Luechau, F., Ling, T.C., Lyddiatt, A. (2009) Partition of plasmid DNA in polymer-salt aqueous two phase systems, Separation and Purification Technology 66, 397 404. (ISI-Cited Publication)

Luechau, F., Ling, T.C., Lyddiatt, A. (2009) Primary capture of high molecular weight nucleic acids using aqueous two-phase systems, Separation and Purification Technology, 66, 202 207. (ISI-Cited Publication)

Luechau, F., Ling, T.C., Lyddiatt, A. (2009) Interfacial partition of plasmid DNA in aqueous two- phase systems, Separation and Purification Technology, 67, 64 70. (ISI-Cited Publication)

Chong, F.C., Tan, W.S., Awang Biak, D.R., Ling, T.C., Tey, B.T. (2009) Purification of histidine-tagged nucleocapsid protein of Nipah virus using immobilised metal affinity chromatography, Journal of Chromatography B, 877, 1561 1567. (ISI-Cited Publication)

Rattana, W., Tey, B.T., Tan, W.S., Taip, F.S., Mustapa Kamal, S.M., Ling, T.C (2009), Application of dye- ligands affinity adsorbent in capturing of rabbit immunoglobulin G, Biochemical Engineering Journal, 45, 232 238. (ISI-Cited Publication)

Luechau, F., Ling, T.C., Lyddiatt, A. (2009) Selective partition of plasmid DNA and RNA in aqueous two-phase systems by the addition of neutral salt, Separation and Purification Technology, 68, 114 118. (ISI-Cited Publication)

Chew, F.N., Tan, W.S., Ling, T.C., Tey, B.T. (2009) Single-step purification of the recombinant green fluorescent protein from intact Eschericia coli cells using preparative page, Electrophoresis, 30, 1 7. (ISI-Cited Publication)

Ooi, C.W., Tey, B.T., Hii, S.L., Ariff, A., Hu, S.W., Lan, C.W.J., Juang, R.S., Mustapa Kamal, S.M., Ling, T.C. (2009) Direct purification of lipase from Burkholderia Pseudomallei using aqueous two-phase systems, Biotechnology and Bioprocess Engineering 14, 811 818. (ISI-Cited Publication)

Ooi, C.W., Tey, B.T., Hii, S.L., Ariff, A., H, S.W., Lan, C.W.J., Mustapa Kamal, S.M., Ling, T.C. (2009) Purification of lipase from Burkholderia Pseudomallei with organic solvent/salt based aqueous two-phase systems, Process Biochemistry, 44, 1083 1087. (ISI-Cited Publication)
 
2008

Ho, C.W., Tan, W.S., Kamaruddin, S., Ling, T.C., Tey, B.T. (2008). The release of hepatitis B core antigen from Escherichia coli by batch mode bead milling. Process Biochemistry, 43, 206 212. (ISI-Cited Publication)

Ho, C.W., Tan, W.S., Kamaruddin, S., Ling, T.C., Tey, B.T. (2008) The direct Recovery of Recombinant Hepatitis B Core Antigen (HBcAg) from Disruptate Derived from Continuous Recycling Bead Milling. Biotechnology & Applied Biochemistry, 50, 49 -59. (ISI-Cited Publication)

Ramanan, R.M., Ling, T.C., Ariff, A. (2008) Disruption of large number of E. coli samples by glass beads shaking. Biotechnology and Bioprocess Engineering. 13, 613 - 623 (ISI-Cited Publication)

Ho, C.W., Tan, W.S., Kamaruddin, S., Ling, T.C., Tey, B.T. (2008) Comparative evaluation of different cell disruption methods for the release of recombinant Hepatitis B core antigen from Escherichia coli and its purification. Biotechnology and Bioprocess Engineering, 13, 577 583 (ISI-Cited Publication)

Ng, M.Y.T., Tan, W.S., Abdullah, N., Ling, T.C., Tey, B.T. (2008). Effect of operating modes and biomass concentrations on the recovery of recombinant Hepatitis B core antigen from thermal-treated unclarified Escherichia coli feedstock. Journal of Biotechnology, 138, 74 79 (ISI-Cited Publication)
 
2007

Negrete, A., Ling, T.C., Lyddiatt, A. (2007) Production of adenoviral vectors and its recovery. Process Biochemistry, 42, 1107 1113. (ISI-Cited Publication)

Lan, C.W.J., Ling, T.C., Hamilton, G., Lyddiatt, A. (2007) Production of an anti-MUC1 C595 dbFv antibody fragment in recombinant Escherichia coli. Process Biochemistry, 42, 77 82. (ISI-Cited Publication)

Chow, Y.M., Tey B.T., Ibrahim, M..N., Ariff A, Ling, T.C. (2007) Dye-ligand expanded bed adsorption of G6PDH from highly dense unclarified yeast extract. Process Biochemistry, 42, 444 448. (ISI-Cited Publication)

Lan, C.W.J., Ling, T.C., O'Sullivan, D.A Lyddiatt, A. (2007) Comparison of two matrices for selective recovery of C595 diabody fragment (dbFv) from Escherichia coli lysates. Process Biochemistry, 42, 335 343. (ISI-Cited Publication)

Chong, F.C., Tey, B.T., Cheong, K.H., Mohd. Dom, Z., Satiawihardja, B., Ibrahim, M.N., Abd. Rahman, R., Awang Biak D. R., Ling, T.C. (2007) Rice bran lipase catalyzed esterification of glycerol and palm oil fatty acid distillate in organic solvent. Biotechnology and Bioprocess Engineering, 12, 250 256. (ISI-Cited Publication)

Negrete, A., Ling, T.C., Lyddiatt, A. (2007) Aqueous two-phase recovery of bio-nanoparticle: A potential miniaturization study for the recovery of bacteriophage T4. Journal of Chromatography B, 854, 13 19. (ISI-Cited Publication)

Ng, M.Y.T., Tan, W.S., Abdullah, N., Ling, T.C., Tey, B.T. (2007). Direct purification of recombinant hepatitis B core antigen from pre-conditioned unclarified Escherichia coli feedstock via expanded bed adsorption chromatography. Journal of Chromatography A, 1172, 47 56. (ISI-Cited Publication)
 
2006

Tan, Y.P., Ling, T.C., Yusoff, K., Tan, W.S., Tey, B.T. (2006). Purification of recombinant nucleocapsid protein of Newcastle disease virus from unclarified feedstock using expanded bed adsorption chromatography. Protein Expression and Purification, 46, 114-121. (ISI-Cited Publication)

Tan, Y.P., Ling, T.C., Yusoff, K., Tan, W.S., Tey, B.T. (2006). Recovery of histidine-tagged nucleocapsid protein of Newcastle disease virus using immobilised metal affinity chromatography. Process Biochemistry, 41, 874-881. (ISI-Cited Publication)

Ling, T.C., Lyddiatt, A. (2006). Effect of polymer shielding on elution of G3PDH bound to dye-ligand adsorbent. Biotechnology and Bioprocess Engineering, 11, 84-87. (ISI-Cited Publication)

Tey, B.T., Chua, M.I., Chua, G.S., Ng M.Y.T, Biak, D.R.A., Tan, W.S., Ling, T.C.(2006) Production of Hepatitis B core antigen in Escherichia coli in stirred tank bioreactor: The influence of temperature and agitation. Biotechnology and Bioprocess Engineering, 11, 164 -167. (ISI-Cited Publication)

Ho, C.W., Chew, T.K., Ling, T.C., Tan, W.S., Kamarruddin, S., Tey, B.T. (2006).Efficient Mechanical Cell Disruption of Escherichia coli by an Ultrasonicator and Recovery of Intracellular Hepatitis B Core. Process Biochemistry, 41, 1829-1834. (ISI-Cited Publication)

Chow, Y.M., Tey, B.T., Ibrahim, M.N., Ariff, A., Ling, T.C. (2006) Protein Adsorption and Hydrodynamic Stability of a Dense, Pellicular Adsorbent in High- Biomass Expanded Bed Chromatography. Biotechnology and Bioprocess Engineering, 11, 268 -272. (ISI-Cited Publication)

Chow, Y.M., Tey, B.T., Ibrahim, M.N, Ariff, A., Ling, T.C. (2006) The performance of Anion exchange expanded bed adsorption chromatography on the recovery of G6PDH from unclarified feedstock with high biomass concentration. Biotechnology and Bioprocess Engineering, 11, 466 469. (ISI-Cited Publication)

Ng, M.Y.T., Tan, W.S., Abdullah, N., Ling, T.C., Tey, B.T. (2006). Heat treatment of unclarified Escherichia coli homogenate improved the recovery efficiency of recombinant hepatitis B core antigen. Journal of Virological Methods, 137, 134-139. (ISI-Cited Publication)

Lan, C.W.J., Ling, T.C., Hamilton, G., Lyddiatt A. (2006) A fermentation strategy for anti-MUC1 C595 diabody expression in recombinant Escherichia coli. Biotechnology and Bioprocess Engineering, 11, 425 - 431. (ISI-Cited Publication)
 
2005

Ling, T.C., Lyddiatt, A. (2005). Process intensification of fluidized bed dye-ligand adsorption of G3PDH from unclarified disrupted Yeast: A case study of the performance of a high-density steel- agarose pellicular adsorbent. Protein Expression and Purification, 42, 160 165 (ISI-Cited Publication)

Tan, Y.P., Ling, T.C., Yusoff, K., Tan, W.S., Tey, B.T. (2005) Comparative evaluation of three purification methods for the nucleocapsid protein of Newcastle disease virus from Escherichia coli homogenates. Journal of Microbiology, 43, 295 300. (ISI-Cited Publication)

Ling, T.C., Lyddiatt, A. (2005). Integration of mechanical cell disruption and fluidised bed recovery of G3PDH from unclarified disrupted yeast: A comparative study of the performance of polymer shielded and unshielded dye-ligand chromatography systems. Journal of Biotechnology, 119, 436 448. (ISI-Cited Publication)

Chow, Y.M., Tey B.T., Ibrahim, M.N., Ariff, A., Ling, T.C. (2005) The Influence of Bakers Yeast Cells on Protein Adsorption in Anion Exchange Expanded Bed Chromatography. Biotechnology and Bioprocess Engineering, 10, 280 - 283. (ISI-Cited Publication)

Chow, Y.M., Tey, B.T., Ibrahim, M.N., Ariff, A., Ling, T.C.( 2005) The Disruption of Saccharomyces cerevisiae Cells and Release of Glucose 6-Phosphate Dehydrogenase (G6PDH) in a Horizontal Dyno Bead Mill Operated in Continuous Recycling Mode. Biotechnology and Bioprocess Engineering, 10, 284 - 288. (ISI-Cited Publication)

Chow, Y.M., Tey, B.T., Ibrahim, M.N., Ariff, A., Ling, T.C. (2005) The influence of Bakers Yeast Cells on protein adsorption performance in Dye-Ligand Expanded Bed Chromatography. Biotechnology and Bioprocess Engineering, 10, 552-555. (ISI-Cited Publication)
 
2004

Ling, T.C., Loong, C.K., Tan, W.S., Tey, B. T., Abdullah, W.M.A., and Ariff, A. (2004). Purification of filamentous bacteriophage M13 by expanded bed anion exchange chromatography. Journal of Microbiology, 42, 228-232. (ISI-Cited Publication)

Tey, B. T., Yong, K.H., Ong, H.P., Ling, T.C., Tan, W.S., Ariff, A. (2004). Optimal conditions for hepatitis B core antigen production in shaked flask fermentation. Biotechnology and Bioprocess Engineering, 9, 374-378. (ISI-Cited Publication)
 
2003

Ling, T.C., Lyddiatt, A., Carmichael, I., Purdom, G., Hathi, P., and Levison, P.R (2003). Direct enzyme adsorption from an unclarified microbial feedstock using suspended bed chromatography. Journal of Chromatography A, 989, 109-118. (ISI-Cited Publication)

AREAS OF RESEARCH
(Project title), (Role), (From)-(Until), (Source), (Level).

CHARACTERIZATION OF FUNDAMENTAL MECHANISM AND PARTIONING BEHAVIOR OF IMMUNOGLOBULIN G IN AQUEOUS TWO-PHASE SYSTEMS, Principal Investigator(PI), 01/12/2013, Fundamental Research Grant Scheme (FRGS), 30/11/2015

Improved downstream processing through phase formation and biomolecular partitioning in aqueous two-phase flotation, Co-Investigator, 2013-2015, Fundamental Research Grant Scheme (FRGS), National

Fabricate And Development Of Selective Adsorbent For Adsorption Of Immunoglobulin G, Principal Investigator(PI), 06/09/2013, Postgraduate Research Grant (PPP) - Research, 05/09/2016

De Novo Genome Assembly Of Lichen ( Cladonia Rangiferina), Principal Investigator(PI), 01/01/2013, Postgraduate Research Grant (PPP) - Research, 31/12/2015

Nanoparticles of Selected Mushrooms As Fibrinolytic Agents, Co-Investigator, 2013-2015, Postgraduate Research Grant(PPP), National

Microalgae-based biofuels and biorefinery (SATU Joint Research Scheme), Co-Investigator, 2012-2013, National Cheng Kung University , Taiwan, International

Preparative techniques and mechanisms of formation of nano-sized palm-based bioactive lipids, Co-Investigator, 2012-2014, Fundamental Research Grant Scheme (FRGS), National

An investigation on the specificity and selectivity of lipase towards polyhydroxyalkanoates hydrolysis and the purification of its oligomers, Co-Investigator, 2012-2014, Fundamental Research Grant Scheme (FRGS), National

Direct recovery of lipase from crude microbial feedstock using aqueous two phase systems, -Co-investigator and Co-supervisor, 2011-2013, Geran Penyelidikan Universiti Malaya (UMRG), National

Development of a simplified and cost-effective technique based on aqueous two-phase systems for direct recovery of interferon-α2b from crude E. coli feedstock, -Co-investigator and Co-Supervisor, 2011-2012, Geran Penyelidikan Universiti Malaya (UMRG), National

Development of a simplified and cost-effective technique for recovery of cyclodextrin glucosyltransferase (CGTase), Principal Investigator(PI), 2011-2013, ScienceFund, National

Direct recovery of lipase derived from Burkhoderia Cepacia in recycling aqueous two- phase flotation, Principal Investigator(PI), 2011-2013, Geran Penyelidikan Universiti Malaya (UMRG), National

Construction of Dunaliella salina (microagae) bioreactor system for the production of human tissue plasminogen activator, Co-Investigator, 2011-2013, Fundamental Research Grant Scheme (FRGS), National

AWARDS AND RECOGNITIONS
(Name of Award), (Awarding Institution), (Year Awarded), (Level).

Eramus Mundus Scholarship, Eramus Mundus, 2013

PRESENTATIONS
(Title), (Event), (Date Presented), (Organiser), (Level).
 
Invited Speaker

EXTRACTIVE BIOCONVERSION OF CYCLODEXTRINS BY BACILLUS CEREUS CYCLODEXTRIN GLYCOSYLTRANSFERASE USING AQUEOUS TWO-PHASE SYSTEM, World biotechnology congress, 03 Jun 2013 to 06 Jun 2013, (International)

PRIMARY PURIFICATION OF BURKHODERIA SP. ST8 LIPASE BY AQUEOUS MICELLAR TWO-PHASE SYSTEM, 2ND WORLD CONGRESS ON BIOTECHNOLOGY, 29 Nov 2011 to 01 Dec 2011, (International)
 
Poster

DIRECT RECOVERY OF LIPASE DERIVED FROM MICROBIAL FEEDSTOCK USING SUSTAINABLE AQUEOUS TWO-PHASE FLOTATION, 17TH INTERNATIONAL CONFERENCE BIOPARTITIONING AND PURIFICATION, 06 Oct 2013 to 10 Oct 2013, (International)

SUPERVISION

 
Post Graduate Level
(Name of Degree), (Name of Candidates), (Title of Thesis), (Academic Session)

Completed

Doctoral Degree (PhD), Ooi Chien Wei, Aqueous two-phase recovery of lipase, 2010/2011

Doctoral Degree (PhD), Chew Few Ne, Production of recombinant green fluorecent protein, 2008/2009

Doctoral Degree (PhD), Sara, Production of lipid, 2007/2008

Doctoral Degree (PhD), Show Pau Loke, Primary capture of lipase, 2010/2011

Doctoral Degree (PhD), Tan Joo Shun, Production of human interferon, 2012/2013

Ongoing

Doctoral Degree (PhD), Zanariah Mohd Dom, Processing of rice bran, 2006/2007

Doctoral Degree (PhD), Chow Yin Hui, Dynamic simulation of protein separation, 2010/2011

Doctoral Degree (PhD), Ng Hui Suan, Recovery of CGTase, 2010/2011

Masters Degree, Nooshin, Recovery Of Lipase From Burkholderia Sp. St8 Using Aqueous Two-Phase System Based On Ionic-Liquid, 2011/2012

Masters Degree, Mastura Abdullah, Profilling Enzymes In Culinary And Medicial Mushrooms, 2011/2012

Masters Degree, Zeinabsadat, Extractive Fermentation Using Recycleable Aqueous Two-Phase System For Purification Of Extracellular Laccase From Pycnoporus Sanguineus, 2011/2012

Doctoral Degree (PhD), Ling Kuok Yong, integrated production, 2011/2012

Masters Degree, Chew Pey Ling, Direct recovery of lipase, 2011/2012

Masters Degree, Linda, Aqueous Two-Phase System For Recovery Of Bioproducts (Laccase) From Liquid Mycelia Medium, 2011/2012

Masters Degree, Nor Hamizah, Purification And Characterization Of Tyrosinase And Laccase In Selected Culinary And Medicinal Mushrooms, 2011/2012
 
First Degree/Diploma/Pre-Degree
(Course Title), (Academic Session), (No. of Candidates)

Ongoing

Final Year Project, 2011/2012, 2

EXPERT LINKAGES
(Linkages Description), (Organisation), (Year of Involvement), (Duration), (Level).

Visiting Professor, University of Xiamen, 2011, 1, (International)

Joint Research Scheme of SATU (National Chen Kung University, Taiwan), Joint Research Scheme of SATU President's Forum, 2012, 1, (International)

Joint Research at Hanoi University of Science and Technology, Hanoi University of Science and Technology, 2012, 1, (International)

Visiting Scholar at Lund University, Sweden, Eramus Mundus Program, 2013, 1, (International)

Fundamental understanding of the roles and mechanism of colloidal zeolite nanoparticles as eco-friendly antioxidants for lubricant oils, FRGS, 2013, 24, (National)

oved downstream processing through phase formation and biomolecular partitioning in aqueous two-phase flotation, FRGS, 2013, 24, (National)

EXPERT/TECHNICAL CONTRIBUTIONS
(Activity), (Organisation), (Role), (From)-(Until), (Level).

Jawatan kuasa Ijazah tinggi Fakulti Sains, Universit Malaya, Committee Member, 2013-2013, (University)

Jawatankuasa Peperiksaan Program Bioteknologi, Universiti Malaya, Committee Member, 2013-2013, (University)

TEACHING
(Course Title), (Academic Session), (No of Student), (No of Contact Hours).


Post Graduate

BIOTECHNOLOGY IN FOOD PRODUCTION, 2011/2012(1), 6, 0

First Degree

MICROBIAL PHYSIOLOGY, 2011/2012(1), 22, 0

SCIENTIFIC COMMUNICATION, 2011/2012(1), 8, 0

MICROBIAL PHYSIOLOGY AND BIOCHEMISTRY, 2011/2012(1), 1, 0

EVALUATION ACTIVITIES
(Description), (Evaluation Activity).

Separation and Purification Technology, Article In Journal

Nonotechnology Development, Article In Journal

Current Biochemical Engineering, Article In Journal

Biotechnology and Bioengineering, Article In Journal

Journal of Bioscience and Bioengineering, Article In Journal

Zainab Binti Ari, Thesis

Process Biochemistry, Article In Journal

Journal of bioscience and bioengineering, Article In Journal

Universiti Teknologi Malaysia, Thesis

Journal of taiwan institute of chemical engineers, Article In Journal

Biotechnology progress, Article In Journal

Fluid Phase Equilibria, Article In Journal

Penilai bebas untuk kenaikan pangkat ke jawatan profesor madya (UPM),

Carbohydrate polymers, Article In Journal

Umirul Mukminin Kahar, Thesis

Fuel, Article In Journal

Noratiqah Binti Kamsani, Thesis

Journal of virological methods, Article In Journal

Monash University Malaysia (Ramalakshimi), PhD transfer examination

Monash University Malaysia (Mircky Lee), PhD transfer examination

Bioresource Technology, Article In Journal

Penilai bebas untuk kenaikan pangkat ke jawatan profesor madya (UPM),

The Open Biotechnology, Article In Journal

CONTRIBUTION TO SOCIETY
(Contribution To Society), (Level), (Start Date), (End Date).

volunteer, walkathon for education, taman sri serdang, (National), 10-Apr-11

volunteer for selling coupons (Family Fun Fair at Taman Sri Serdang), (District), 16-Oct-11

Visiting professor (Xiamen University, China), (Country), 05-Aug-11 until 26-Aug-11