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CURRICULUM VITAE
PERSONAL DETAIL

Name
  Dr. Retnagowri A/P Rajandram
Designation
  Senior Lecturer
Department
  Department of Surgery
Faculty
  Faculty of Medicine
E-mail Address
  rretnagowri@um.edu.my
Address(Office)
  Department of Surgery, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA

ACADEMIC QUALIFICATION
(Qualification), (Institution).
PHD, THE UNIVERSITY OF QUEENSLAND, AUSTRALIA (2009), UNIVERSITY OF QUEENSLAND, AUSTRALIA
BSC (BIOCHEMISTRY) WITH HONOURS CLASS 1, THE UNIVERSITY OF QUEENSLAND, AUSTRALIA, UNIVERSITY OF QUEENSLAND, AUSTRALIA

PROFESSIONAL AFFILIATION/MEMBERSHIP
(Organisation), (Role), (Year), (Level).

Journal of Cancer Science and Clinical Research, Editorial Board Member, 2014, (International)

UMCRI, Academic, 2011, (International)

Associate Professor Glenda Gobe at CKDR group at Translation Research Institute and University of Queensland, Australia, Research Collaboration, 2011, (International)

ADMINISTRATIVE DUTIES
(Role), (Level), (Start date),(End Date).


Central level JPPGP coordinator , University Malaya, 01-Oct-13 - 31-Jul-15

Research Committee Coordinator , Department Of Surgery, Faculty Of Medicine, 20-Sep-13 - 31-Dec-15

Document Manager, Department Of Surgery, Faculty Of Medicine, 01-Oct-12 - 30-Oct-12

Coordinate Research Meetings in the Department., Department Of Surgery, Faculty Of Medicine, 13-May-10 - 01-Apr-15

CAREER HISTORY
(Post), (Organisation), (Period).


Research Associate, A/PROF.GLENDA RESEARCH GROUP (DISCIPLINE OF MEDICINE), 01/02/2007 until 29/02/2008

RECENT SELECTED PUBLICATIONS
(Publication).
 
Chapter In Book
 
2014

Rajandram R, Ong TA, Saad M. The challenges of drug resistance in renal cell carcinoma. In: Morais, C. ed. Advances in drug resistance research, Nova Science Publishers, N.Y., USA. 
 
Article In Academic Journals
 
2014

Differentiation of oncocytoma from chromophobe renal cell carcinoma (RCC): can novel molecular biomarkers Journal of Clinical Pathology Keng Lim Ng1, 2, Retnagowri Rajandram1, 3, Christudas Morais1, Yap Ning Yi3, Hema Samaratunga4, Glenda C Gobe1, Simon T Wood267(2):97-104 (ISI-Cited Publication)

Bennett N, Rajandram R, Ng KL and Gobe G. (2014). EVALUATION OF STEROID HORMONES AND THEIR RECEPTORS IN DEVELOPMENT AND PROGRESSION OF RENAL CELL CARCINOMA, Journal of Kidney Cancer and VHL (Non-ISI/Non-SCOPUS Cited Publication)

R Rajandram, 5, NY Yap, J Pailoor, AHA Razack, KL Ng, TA Ong,C Morais and GC Gobe (2014). TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED FACTOR-1 (TRAF-1) EXPRESSION IS INCREASED IN RENAL CELL CARCINOMA PATIENT SERUM BUT DECREASED IN CANCER TISSUE COMPARED WITH NORMAL: POTENTIAL BIOMARKER SIGNIFICANCE. Pathology (ISI/SCOPUS Cited Publication)
 
2013

Efficacy of microbial cell preparation in improving chronic constipation: A randomized, double-blind, placebo-controlled trial; clincial nutrition; Jayasimhan S, Yap NY, Roest R, Rajandram R, Chin KF (ISI/SCOPUS Cited Publication)

Yap NY, Ng KL, Ong TA, Pailoor J, Gobe GC, Ooi CC, Razack AH, Dublin N, Morais C, Rajandram R. Evaluation of clinical prognostic factors and survival outcome of Renal Cell Carcinoma patients -a Malaysian single centre perspective.2013. Asian Pac J Cancer Prev. 2013;14(12):7497-500. (ISI-Cited Publication)

Chromosome 7 aneuploidy in clear cell and papillary renal cell carcinoma: detection using silver-in-situ hybridisation technique Jayalakshmi Pailoor, Retnagowri Rajandram, Ning Yi Yap, Keng Lim Ng, Zhiqiang Wang, Krishnan R. Iyengar Indian Journal of Pathology and Microbiology (ISI-Cited Publication)
 
2012

Rajandram R, Bennett N, Morais C, Johnson DW, Gobe G. Renal cell carcinoma: Resistance to therapy, role of apoptosis, and the prognostic and therapeutic target potential of TRAF proteins. Medical Hypotheses 78(2): 330-336. (ISI-Cited Publication)

Rajandram R, Bennett N, Wang Z, Perry-Keene J, Vesey D, Johnson DW, Gobe G. Patient samples of renal cell carcinoma show reduced expression of TRAF1 compared with normal kidney and functional studies in vitro indicate TRAF1 promotes apoptosis: potential for targeted therapy. (Manuscript accepted for publication by Pathology; Manuscript No.: PAT_D_11_00296) (ISI-Cited Publication)
 
2009

Rajandram R, Pat BK, Li J, Johnson DW, Gobe GC. 2009. Expression of apoptotic tumour necrosis factor receptor-associated factor, caspase recruitment domain and cell death-inducing DFF-45 effector genes in therapy-treated renal cell carcinoma. Nephrology 2: 205-212. (ISI-Cited Publication)
 
Extended Abstract
 
2014

Retnagowri Rajandram1, Ning Yi Yap, Jayalakshmi Pailoor, Azad H.A. Razack, Keng Lim Ng, Christudas Morais and Glenda Gobe(2014). Serum TRAF-1 as a biomarker for developing clear cell renal cell carcinoma. Journal of Molecular Biomarkers & Diagnosis. April 2014, 5(2):p42 .Proceeding of 5th International Conference on Biomarkers and Clinical Research (ISI/SCOPUS Cited Publication)

R Rajandram, NY Yap, J Pailoor, AHA Razack, KL NG, C Morais and G Gobe. 2014. Investigation of tumour necrosis factor receptor-associated factor 1 expression in renal cell carcinoma from a single asian centre. BJU International volume 113, Supplement 4 : 51-137 (ISI/SCOPUS Cited Publication)

NY Yap, KL Ng, TA Ong, J Pailoor, AHA Razack, G Gobe, C Morais and R Rajandram. 2014. Clinical data as prognostic tools in the management of renal cell carcinoma (RCC). BJU International volume 113, Supplement 4 : 51 137 (ISI/SCOPUS Cited Publication)

T.A. ONG, K.S. MUN, P. JAYASIMHAN, N.Y. YAP, H.A.M. WALI, A.H.A. RAZACK, R. RAJANDRAM, and M.A. MOHD. 2014. Pathological changes of the urinary tract from chronic oral ketamine and its reversibility in a rat model. BJU International volume 113, Supplement 4 : 51-137 (ISI/SCOPUS Cited Publication)
 
2013

Rajandram R, NY Yap, J Pailoor, AHA Razack, KL NG, G Gobe C Morais (2013). Molecular Characteristics of Renal Cell Carcinoma- a study using TRAF1 and Malaysian patient cohort. Nephrology 18(suppl 1.) p47 (ISI-Cited Publication)

NY Yap, R Rajandram, J Pailoor, AHA Razack, TA Ong, KL Ng, C Morais and G Gobe. 2013. Evaluating the characteristics of newly diagnosed Renal Cell Carcinoma to improve patient outcome. 18 (suppl. 1):34. (ISI-Cited Publication)
 
2012

Rajandram, R., Gobe, G., Wang, Z., Vesey, D. A., Johnson, D. W. and Morais, C. (2012). Increasing anti- apoptotic nucleolar protein-3 correlates with cancer progression in renal cell carcinoma. In: , Special Issue: Abstracts of the 48th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology. 48th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Auckland, New Zealand, (59-59). 27 - 9 August 2012. (ISI/SCOPUS Cited Publication)

Ng K L, Ong T A, Yap N Y, Mun K S, Mohamad Ali HA, Ali Mohd M, Razack A H, Rajendram R, Hasan M S. 2012. Histopathological changes to the urinary tract induced by oral ketamine in a rat model. Medical Journal Malaysia 2012, 67(2) Abstract 33 - 20th Malaysian Urological Conference-Asia Pacific Society of Uro- Oncology Conference (SCOPUS-Cited Publication)

Pailoor Jayalaksmi, Retnagowri Rajandram, Krishnan Iyengar and Azad Razack. Renal cell carcinoma: Silver In Situ Hybridisation Detection of Chromosome 7 Abnormalities. Medical Journal Malaysia 2012, 67(2) Abstract 2 - 20th Malaysian Urological Conference-Asia Pacific Society of Uro-Oncology Conference (SCOPUS-Cited Publication)

Rajandram R, Ng KL, Htun TH, Ong TA and Razack AH. Analyses of the outcome of patients presenting to UMMC with renal cell carcinoma. Medical Journal Malaysia 2012, 67(2) Abstract 4 - 20th Malaysian Urological Conference-Asia Pacific Society of Uro-Oncology Conference (SCOPUS-Cited Publication)

Retnagowri Rajandram, Nigel C. Bennett, Zhiqiang Wang, Joanna Perry-Keene, David A. Vesey, David W. Johnson and Glenda C. Gobe. Tumour necrosis factor receptor- associated factor 1 (TRAF1) has a functional role in renal carcinoma (RCC) apoptosis, has decreased expression in RCC samples, and may have potential for targeted therapy. Medical Journal Malaysia 2012, 67(2) Abstract 5 - 20th Malaysian Urological Conference-Asia Pacific Society of Uro-Oncology Conference (SCOPUS-Cited Publication)
 
2010

Vesey, D., Rajandram, R., Blakeney, J., Suen, J., Johnson, D., Fairlie, D. and Gobe, G. (2010). Protease-activated receptor-2 and renal carcinogenesis. In: 46th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth Convention and Exhibition Centre, Perth, Western Australia, (91-91). 12-15 September 2010. (ISI-Cited Publication)
 
2009

Gobe, Glenda C., Rajandram, Retnagowri, Vesey, David A., Wang, Zhiqiang, Bennett, Nigel and Johnson, David W. (2009). Functional significance of TRAF1 knockdown in renal cell carcinoma anti-cancer treatment. In: , Journal of the American Society of Nephrology. Abstract Issue of the 2009 Annual Meeting of the American Society of Nephrology. American Society of Nephrology Renal Week: 42nd Annual Meeting & Scientific Exposition, San Diego, CA, U.S.A., (605A- 605A). 27 October - 1 November, 2009. (ISI-Cited Publication)
 
2008

Rajandram R, Perry-Keene J, Campbell C, Johnson D and Gobe G. Immunohistochemical profiling of clear cell renal cell carcinoma a tissue microarray study. 44th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology. Nephrology 13, suppl. 3, September 2008 (ISI-Cited Publication)
 
2006

Rajandram R, Pat B, Li J, Percy C, Vesey D, Johnson D and Gobe G. Resistance to cancer treatments in renal cell carcinomas: discovering novel apoptosis pathways. 42nd Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology. Nephrology 11, suppl. 2, August 2006 (ISI-Cited Publication)

AREAS OF RESEARCH
(Project title), (Role), (From)-(Until), (Source), (Level).

Expression of inflammatory markers in cerebral arteriovenous malformation (AVM) subjects: a correlation between patient tissues and blood samples, Co-Investigator, 2014-2015, Fundamental Research Grant Scheme (FRGS), National

Biomarker discovery in Renal Cell Carcinoma (RCC), Principal Investigator(PI), 01/01/2014, Science Fund, 31/12/2015

TRAF1 and NF-kB : Understanding and evaluating the molecular mechanisms and therapeutic potential in renal cell carcinoma, Principal Investigator(PI), 08/10/2013, Geran Penyelidikan Universiti Malaya (UMRG) - HTM (Wellness), 08/10/2014

DECIPHERING THE MOLECULAR MECHANISMS AND THERAPEUTIC POTENTIAL OF TRAF1 AND NF-KB IN RENAL CELL CARCINOMA, Principal Investigator(PI), 01/12/2013, Fundamental Research Grant Scheme (FRGS), 31/10/2015

TRAF1 and NF-kB:Understanding and evaluating the molecular mechanisms and therapeutic potential in renal cell carcinoma, Principal Investigator(PI), 2013-2014, Geran Penyelidikan Universiti Malaya (UMRG), National

Urinary tract and liver injury from long term oral ketamine and its reversibility in a rat model., Co-Researcher, 19/06/2012, Geran Penyelidikan Universiti Malaya (UMRG) - HTM (Wellness), 18/12/2014

Caspase-8 and TRAF1 as biomarkers of progression of Renal Cell Carcinomas, Principal Investigator(PI), 2012-2013, Geran Penyelidikan Universiti Malaya (UMRG), National

Urinary tract and liver injury from long term oral ketamine and its reversibility in a rat model., Co-Investigator, 2012-2013, Geran Penyelidikan Universiti Malaya (UMRG), National

Caspase-8 and TRAF1 as biomarkers of progression of Renal Cell Carcinomas, Principal Investigator(PI), 2011-2012, Geran Penyelidikan Universiti Malaya (UMRG), National

Screening of genetic markers in Prostate Cancer in The Malaysian Population, Co-Investigator, 2010-2011, Geran Penyelidikan Universiti Malaya (UMRG), National

CONSULTATION PROJECT/CONSULTANCY
(Project title), (Role), (From)-(Until), (Organisation).

Endothelial cells in brain arteriovenous malformation (AVM), Researcher, 2013-2016, Australian School of Advanced Medicine, Macquarie University, Sydney

PRESENTATIONS
(Title), (Event), (Date Presented), (Organiser), (Level).
 
Invited Speaker

Retnagowri Rajandram, Zhiqiang Wang, Joanna Perry-Keene, David Johnson and Glenda Gobe. Investigation of TNF receptor associated factor -1 (TRAF1) biomarker potential for Renal Cell Carcinoma (RCC), Malaysian Urology Research Seminar 2011, 23 Feb 2011 to 23 Feb 2011, Urology Unit, Department of Surgery, Faculty of Medicine, University of Malaya, (National)

Retnagowri Rajandram, Zhiqiang Wang, Joanna Perry-Keene, David Johnson and Glenda Gobe. Improving molecular signatures to characterize renal cell carcinoma a study using tissue microarray invited oral presentation. , January 2011., GTCbio's 3rd Oncology Biomarker Conference, 28 Jan 2011 to 28 Jan 2011, GTCbio, (International)
 
Oral

MOLECULAR CHARACTERISTICS OF RENAL CELL CARCINOMA - A STUDY USING TRAF-1 AND A MALAYSIAN PATIENT COHORT Retnagowri Rajandram, Ning Yi Yap, Jayalakshmi Pailoor, Azad H.A. Razack, Keng Lim Ng Christudas Morais and Glenda Gobe -ORAL PRESENTATOR, Australian and New Zealand Society of Nephrology 49th Annual Scientific Meeting, 09 Sep 2013 to 11 Sep 2013, (International)

EVALUATING THE CHARACTERISTICS OF NEWLY DIAGNOSED RENAL CELL CARCINOMA TO IMPROVE PATIENT OUTCOME Ning Yi Yap, Retnagowri Rajandram Jayalakshmi Pailoor Azad H.A. Razack Teng Aik Ong Keng Lim Ng, Christudas Morais and Glenda Gobe, Australian and New Zealand Society of Nephrology 49th Annual Scientific Meeting, 09 Sep 2013 to 11 Sep 2013, (International)

Retnagowri Rajandram1, Ning Yi Yap, Jayalakshmi Pailoor, Azad H.A. Razack, Keng Lim Ng, Christudas Morais and Glenda Gobe. Serum TRAF-1 as a biomarker for developing clear cell renal cell carcinoma, 5th International Conference on Biomarkers and Clinical Research, 15 Apr 2014 to 17 Apr 2014, Omics Group, (International)

Cardiac automatic neuropathy, a major of left ventricular Dysfunction?, 26th scientific meeting of malaysian society of pharmacology and physiology (translational research for sustainable wellness: from perception to reality), 18 May 2012 to 20 May 2012, MSPP, (International)
 
Poster

Teng Aik Ong, Kein Seong Mun, Pushpa Jayasimhan, Ning Yi Yap, Haryanti A. Mohamad Wali, Azad H. Abdul Razack, Retnagowri Rajandram1, Mustafa Ali Mohd. Pathological changes of the urinary tract from chronic oral ketamine and its reversibility in a rat model, 67th Urological Society of Australia and New Zealand Annual Scientific Meeting, 17 Mar 2014 to 19 Mar 2014, Urological Society Australia and New Zealand, (International)

Ning Yi Yap, Keng Lim Ng, Teng Aik Ong, Jayalakshmi Pailoor, Azad H.A. Razack, Glenda Gobe, Christudas Morais and Retnagowri Rajandram Clinical data as prognostic tools in the management of renal cell carcinoma (RCC), 67th Urological Society of Australia and New Zealand Annual Scientific Meeting, 17 Mar 2014 to 19 Mar 2014, Urological Society of Australia and New Zealand, (International)

A new simple non-invasive method for assessing autonomic function test, 26th scientific meeting of malaysian society of pharmacology and physiology (translational research for sustainable wellness: from perception to reality), 18 May 2012 to 20 May 2012, MSPP, (International)

Retnagowri Rajandram1,2, Glenda Gobe2, Zhiqiang Wang3, David Vesey2,4, David W Johnson2,4 And Christudas Morais2 Increasing Nucleolar Protein-3 Correlates With Cancer Progression In Renal Cell Carcinoma. Anzsn Scientific Meeting, Auckland, New Zealand August 2012, INCREASING ANTI-APOPTOTIC NUCLEOLAR PROTEIN-3 CORRELATES WITH CANCER PROGRESSION IN RENAL CELL CARCINOMA RETNAGOWRI RAJANDRAM1,2, GLENDA GOBE2, ZHIQIANG WANG3, DAVID VESEY2,4, DAVID W JOHNSON2,4 AND CHRISTUDAS MORAIS2 48th Australian and New Zealand Society of Nephrology Annual Scientific Meeting,, 25 Aug 2012 to 26 Aug 2012, Australian and New Zealand Society of Nephrology, (International)

Rajandram R, Ng KL, Htun TH, Ong TA and Razack AH. Analyses of the outcome of patients presenting to UMMC with renal cell carcinoma., 20th Malaysian Urological Conference-Asia Pacific Society of Uro-Oncology Conference;, 25 Nov 2011 to 27 Nov 2011, Malaysian Urological Association Suite 2-5 2nd Floor Medical Academies of Malaysia, (National)

Pailoor Jayalaksmi, Retnagowri Rajandram, Krishnan Iyengar and Azad Razack. Renal cell carcinoma: Silver In Situ Hybridisation Detection of Chromosome 7 Abnormalities., 20th Malaysian Urological Conference-Asia Pacific Society of Uro-Oncology Conference; Moderated poster., 25 Nov 2011 to 27 Nov 2011, Malaysian Urological Association, (National)
 
Presenter

Retnagowri Rajandram, Ning Yi Yap, Jayalakshmi Pailoor, Azad H.A. Razack, Keng Lim Ng, Christudas Morais and Glenda Gobe. Investigation of tumour necrosis factor receptor-associated factor 1 expression in renal cell carcinoma from a single Asian centre, 67th Urological Society of Australia and New Zealand Annual Scientific Meeting, 17 Mar 2014 to 19 Mar 2014, Urological Society of Australia and New Zealand, (International)
 
Others

Master of Ceremony, 3rd Asia-Pacific Gastro-phageal Cancer Congress, 10 Nov 2011 to 12 Nov 2011, College of Surgeons, AMM, (International)

Vesey DA, Rajandram R, Blakeney J, Suen J, Johnson D, Fairlie D, Gobe G. Protease-activated receptor-2 and renal carcinogenesis Nephrology(Carlton) 2010: 15, Suppl 4; Abstr 246., 46th Annual Scientific Meeting ANZSN, 12 Sep 2010 to 15 Sep 2010, AUSTRALIAN AND NEW ZEALAND SOCIETY OF NEPHROLOGY, (International)

Retnagowri Rajandram, Nigel C. Bennett, Zhiqiang Wang, Joanna Perry-Keene, David A. Vesey, David W. Johnson and Glenda C. Gobe. Tumour necrosis factor receptor-associated factor 1 (TRAF1) has a functional role in renal carcinoma (RCC) apoptosis, has decreased expression in RCC samples, and may have potential for targeted therapy. Conference; Moderated poster. Shangri-La Hotel, Kuala Lumpur, Malaysia, November 2011., 20th Malaysian Urological Conference-Asia Pacific Society of Uro-Oncology Conference, 25 Nov 2011 to 27 Nov 2011, Malaysian Urological Association Suite 2-5 2nd Floor Medical Academies of Malaysia, (National)

SUPERVISION

 
Post Graduate Level
(Name of Degree), (Name of Candidates), (Title of Thesis), (Academic Session)

Completed

Masters Degree, Lai Jiun Yee, The phenotypic effects of in vitro miR141 expression modulation in Bladder Cancer, 2012/2013

Masters Degree, Tan Peng Chiang, Cardiac Autonomic Neuropathy In Young Patients With Type-2 Diabetes Mellitus, 2011/2012

Ongoing

Masters Degree, Narendra Balasekaran, CSF INFLAMMATORY MARKERS AS A PREDICTOR OF CEREBRAL VASOSPASM AND FUNCTIONAL OUTCOME IN SAH FOLLOWING RUPTURED INTRACRANIAL ANEURYSM : A SINGLE INSTITUTION EXPERIENCE, 2012/2013

Masters Degree, Narendra Balasekaran, CSF INFLAMMATORY MARKERS AS A PREDICTOR OF CEREBRAL VASOSPASM AND FUNCTIONAL OUTCOME IN SAH FOLLOWING RUPTURED INTRACRANIAL ANEURYSM : A SINGLE INSTITUTION EXPERIENCE, 2013/2014

EXPERT/TECHNICAL CONTRIBUTIONS
(Activity), (Organisation), (Role), (From)-(Until), (Level).

Basic Statistical help, MSurg student at University of Malaya, Expert Advisor, 2014-2014, (Individual)

Sample size calculation, Masters of Surgery Student, Expert Advisor, 2014-2014, (Individual)

Manuscript preparation advice, University of Malaya Masters Student, Expert Advisor, 2014-2014, ()

Reviewer for: Effects of Streptococcus thermophilus TH-4 in a Rat Model of Doxorubicin-Induced Mucositis", Scandinavian Journal of Gastroenterology., Invited Reviewer, 2013-2013, (International)

Reviewer for: effect of yogurt containing polydextrose, Lactobacillus acidophilus NCFM and Bifidobacterium lactis HN019: a randomized, double-blind, controlled study in chronic constipation; invited reviewer, 2014 Nutrition Journal (International), Nutrition Journal, Reviewer, 2014-2014, (International)

Reviewer for: Short-term effect of fresh pomegranate juice on levels of fasting serum glucose and insulin in type 2 diabetic patients Nutrition Research, Nutrition Journal, Reviewer, 2014-2014, (International)

TEACHING
(Course Title), (Academic Session), (No of Student), (No of Contact Hours).


Post Graduate

Introduction to Statistics, 2011/2012(2), 15, 3

Surgery LAB SET UP task set by Head of Department, 2011/2012(1,2,3), 10, 200

Surgery LAB SET UP task set by Head of Department, 2010/2011(1,2,3), 10, 60

Surgery LAB SET UP task set by Head of Department, 2013/2014(1,2,3), 12, 200

Surgery LAB SET UP task set by Head of Department, 2012/2013(1,2,3), 12, 200

Diploma (If Applicable)

Immunology, 2012/2013(1), 28, 11

Immunology, 2010/2011(1), 24, 7

Immunology, 2013/2014(1,2), 28, 22