|RECENT SELECTED PUBLICATIONS
| Article In Academic Journals |
| 2012 |
I.-C. Sam, R. Karunakaran, A. Kamarulzaman, S.
Ponnampalavanar , S.F. Syed Omar, K.P. Ng, M.Y. Mohd
Yusof, P.S. Hooi, F.L. Jafar , S. AbuBakar. A large
exposure to Brucella melitensis in a diagnostic
laboratory. J Hosp Infect. 2012; 80: 321-325.
Ng KP, Ngeow YF, Yew SM et al. Draft Genome Sequence
of Daldinia eschscholzii Isolated from Blood Culture.
Eukaryot Cell 2012 (in-Press).
K P Ng, YF Ngeow, SM Yew, Hamimah Hassan, TS Soo-Hoo
et al. Sequencing of Cladosporium sphaerospermum, A
Dematiaceous Fungus Isolated from Blood Culture.
(Accepted by Eukaryot Cell, March 2012).
Ng KP, Yew SM, Chan CL, Soo-Hoo TS, Na SL, Hassan H, Ngeow YF, Hoh CC, Lee KW, Yee WY. Genome Sequencing of An Unclassified Pleosporales species Isolated from Human Nasopharyngeal Aspirate. Eukaryotic cells 2012;11(6):828. (ISI/SCOPUS Cited Publication)
Wong YL, Choow SW, Tan Jl, Ong Cs, Ng KP. Draft Genome Sequence of Mycobacterium bolletti Strain M 24, a rapidly growing Mycobacterium of Contentious Taxonomic Status. J Bacteriol. 2012 Aug;194(16):4475
Siew Woh Choo, Aini Mohamed Yusoff, Yan Ling Wong, Wei Yee Wee, Chia Sui Ong, Kee Peng Ng and Yun Fong Ngeow. 2012. Genome analysis of Mycobacterium massiliense strain M172 with a putative mycobacteriophage. J Bacteriol 2012;194(18):5128
| 2011 |
Proteinase, phospholipase, biofilm forming abilities
and antifungal susceptibilities of Malaysian Candida
isolates from blood cultures.
Tay ST, Abidin IA, Hassan H, Ng KP.
Med Mycol. 2011 Jan 24. [Epub ahead of print] (ISI-Cited Publication)
Alireza Khodavandi, Fahimeh Alizadeh, Nabil S Harmal,
Shiran M Sidik, Fauziah Othman, Zamberi Sekawi,
Mohammad Ali Farboodniay Jahromi, Kee-Peng Ng, Pei Pei
Chong. Comparison between efficacy of allicin and
fluconazole against Candida albicans in vitro and in a
systemic candidiasis mouse model. FEMS Microbiol Lett.
2011; 315(2):87-93 (SCOPUS-Cited Publication)
Yun Fong Ngeow, Yan Ling Wong, Kee Peng Ng, Chia Sui
Ong, Wah Wah Aung Rapid, Cost-Effective Application of
Tibilia TM TB for the Confirmation of Live and Heat-
Killed Mycobacterium tuberculosis. J Clin Microbiol.
| 2009 |
Phelim Yong, Ong Khang Wei, Ng Kee Peng, Rozita Rosli,
Shiran Md. Sidek, Chong Pei Pei. A modified in situ RT-
PCR method for localizing fungal-specific gene
expression in Candida-infected mice renal cells. J
Microbiol Methods.2009; 79(2): 242-245 (ISI-Cited Publication)
| 2008 |
J.M.Jee, P.P.Chong, K.P.Ng, C.C.Ho, H.F. Seow.
Antifungal Properties of Secondary Metabolites from a
Streptomyces species. Int J Infect Dis. 2008; 12: E285-
E286. (ISI-Cited Publication)
Lau KA, Wang B, Kamarulzaman A, Ng KP, Saksena NK.
Continuous Crossover (s) Events of HIV-1 CRF01_Ae and
B Subtype Strains in Malaysia: Evidence of Rapid and
Extensive HIV-1 Evolution in the Region . Curr HIV Res
2008; 6 (2): 108-116. (ISI-Cited Publication)
Pfaller MA, Diekema DJ, Gibbs DL, Newell VA, NaGY e,
Dobiasova S, Rinaldi M, Barton R, Veselov A, Ng KP.
The Global Antifungal Surveillance Group. Candida
krusei, a multidrug-resistant fungal pathogen:
Geographical temporat trends from the ARTEMIS Disk
antifungal Surveillance Program. J Clin Microbiol
2008; 46(3):842-849. (ISI-Cited Publication)
| 2007 |
R Karunakaran, NS Raja, KP Ng, P Navaratnam. Etiology
of blood culture isolates among patients in a
multidisciplinary teaching hospital in Kuala Lumpur.
J Microbiol Immunol Infect 2007; 40: 432-437
Madhavan, P., Jamal, P., Chong, PP. & Ng KP. In-vitro
activity of fluconazole and voriconazole against
clinical isolates of Candida spp. By E-test method.
Trop Biomed 2010; 27(2):200-2007.
Than Leslie, TL, Chong PP, Ng, KP, Seow , HP.
Detection of different medically important Aspergillus
species involved in invasive aspergillosis through DNA
microarray with tyramidee signal amplification.
Malaysian J Med Health Sci. 2007; 3(1): 27.
Wang YM, Wang B, Dyer WB, Lachireddy K, Peng NK,
Saksena NK. Evidence for predominance of CCR5 HIV-1
strains during highly active antiretroviral therapy.
Curr HIV Res. 2007; 5(2): 221-34.
Wang YM, Dyer WB, Workman C, Wang B, Peng NK,
Lachireddy K, Chew CB, Sullivan J, Saksena NK. Drug
resistance and viral evolution in plasma and
peripheral blood cells during structured treatment
interruption (STI) and non-interrupted HAART. Curr HIV
Res. 2007; 5(2):235-50.
Wang B, Lau KA, Ong LY, Shah M, Steain MC, Foley B,
Dwyer DE, Chew CB, Kamarulzaman A, Ng KP, Saksena NK.
complex patterns of the HIV-1 epidemic in Kuala
Lumpur, Malaysia: evidence for expansion of
circulating recombinant form CRF33_01B and detection
of multiple other recombinants. Virology. 2007; 367
Lau KA, Wang B, Kamarulzaman A, Ng KP, Saksena NK.
Near full-length sequence analysis of a Unique
CRF01_AE//B recombinant from Kuala Lumpur, Malaysia.
AIDS Res Hum Retroviruses 2007; 23(9): 1139-45. (ISI-Cited Publication)
Pfaller MA, Diekema DJ, Gibbs DL, Ng KP. Newell VA.
Results from the Artemis Disk Global Antifungal
Surveillance Study, 1997-2005 ; An 8.5 year analysis
of susceptibilities of Candida and other yeast species
to fluconazole and voriconazole by CLSI standardized
disk diffusion testing. J Clin Microbiol 2007; 45:1735-
45. (ISI-Cited Publication)
Pei Pei Chong, Abdul Hadi Siti Rohani, Yee Lean Lee,
Chin Lee Phan, Oon Chong Tan, Kee Peng Ng, Heng Fong
Seow. Genotyping and drug resistance profile of
Candida species in recurrent and one-off vaginitis and
high association of non-albicans species with non-
pregnant status infection. Infect Genet Evol. 2007; 7
(4):449-56 (ISI-Cited Publication)
Bin Wang, Katherine A, Lai-Yee Ong, Meet Shah, Megan,
C.Steain, Brian Foley, Dominic E.Dwyer, Choo Beng
Chew, Adeeba Kamarulzaman, Kee Peng Ng and Nitin
K.Saksena. Complex Patterns of HIV Epidemic in Kuala
Lumpur. Form CRF33_01B. J Virol. 2007; 367: 288-297 (ISI-Cited Publication)
Siti-Rohani, A.H., Lee, Y.L., Tan, B.C. , Ng, K.P.,
Seow, H.F., Chong, P.P. Molecular genotyping of
Candida isolates from vaginitis patients in Malaysia:
implications in management of recurrent vaginitis.
Infect Genet Evol. 2007; 7: 449-456.
YUAN MIN WANG, BIN WANG, KISHEN LACHIREDDY, NG KEE
PENG, NITIN K. SAKSENA. HIV-1 Co-receptor dynamics in
T-lymphocytes during interrupted and non-interrupted
HAART: Mechanism for the emergence of less pathogenic
HIV-1 strains. Res. 2007; 5 (2): 221-34 (ISI-Cited Publication)
| 2006 |
Tee KK, Li XJ, Nohtomi K, Ng KP, Kamarulzaman A,
Takebe Y. Identification of a novel circulating
recombinant form (CRF33_01B) disseminating widely
among various risk populations in Kuala Lumpur,
Malaysia. J Acquir Immune Defic Syndr 2006; 43(5):523-
529. (ISI-Cited Publication)
Tee KK, Kamarulzaman A, Ng KP. Prevalence and pattern
of drug resistance mutations among antiretroviral-
treated HIV-1 patients with suboptimal virological
response in Malaysia. Med Microbiol Immunol 2006; 195
(2):107-112. (ISI-Cited Publication)
Cheang, PY, Chong, PP, Mariana, NS, Ng, KP. Cloning
of Phospholipase B Gene Homologues in Candida species
via Degenerate PCR. Biomed Res. 2006; 17(1): 117-123. (ISI-Cited Publication)
S.T. Tay, Tanty Haryanty, K.P. Ng. M.Y. Rohani & H.
Hamimah. In vitro susceptibilities of Malaysian
clinical isolates of Cryptococcus neoformans var.
grubii and Cryptococcus gattii to five antifungal
drugs. Mycoses 2006; 49:324-330. (ISI-Cited Publication)
V.C. Yong. L.M. Chew, C.L. Kwan, K.P. Ng, H.F. SEow, &
P.P. Chong. Transcriptional and sequencing analysis of
CtCDR1, CtMDR1 and CtERG11 genes in fluconazole-
resistance Candida tropicalis isolates from candidemia
patients. J Med Sci., 2006; 6(5): 713-723 (ISI-Cited Publication)
52.Pei Pei Chong, David Ching-Soo Chieng, Lee
Yean Low, Asma Hafeez, Mariana Nor Shamsudin, Heng
Fong Seow & Kee Peng Ng. Recurrent candidaemia in a
neonate with Hirschsprung s disease: fluconazole
resistance and genetic relatedness of eight Candida
tropicalis isolates. J Mol Microbiol 2006; 55: 423-428 (ISI-Cited Publication)
Soo Fen Wong, Boon Chong Tan, Siti Rohani bt Abdul
Hadi, Kee Peng Ng & Pei Pei Chong. Rapid diagnosis of
Candida albicans vaginitis directly from high vaginal
swabs. Int J Mol Adv Sci 2006; 2(3): 239-244. (ISI-Cited Publication)
Kok Keng Tee, Adeeba Kamarulzaman, Kee Peng Ng.
Prevalence and pattern of drug resistance mutations
among antiretroviral-treated HIV-1 patients with
suboptimal virological response in Malaysia Med
Microbiol Immunol 2006; 195(2):107-112. (ISI-Cited Publication)
M Pfaller, D Diekema, A Colombo, C Kibler, KP Ng, D
Gibbs, V Newell & Global Antifungal Surveillance
group. Candida rugosa, an emerging fungal pathogen
with resistance to Azoles: geographic and temporal
trends from ARTEMIS Disck antifungal Surveillance
program. J Clin Microbiol 2006; 44: 3578-3582 (ISI-Cited Publication)
Chong PP, Cheang DCS, Shamsudin MN, Seow HF, Ng KP,
Chong PP. Recurrent candidemia in a neonate with
Hirchsprung s disease fluconazole resistance and
genetic relatedness of eight Candida tropicalis
isolates. J Med Microbiol 2006; 55 (4): 423-428. (ISI-Cited Publication)
| 2005 |
Ng Kee Peng, "Impact of Expanded Program of
Immunization on Hepatitis B infection in school
children in Malaysia. Medical Microbiology and
Immunology", 2005, Vol. 194, pg. 163-168, (ISI-Cited Publication)
Tee KK, Saw TL, Pon CK, Kamarulzaman A, Ng KP.
The evolving molecular epidemiology of HIV type 1
among injecting drug users (IDUs) in Malaysia.
AIDS Res Hum Retroviruses. 2005 Dec;21(12):1046-50.
S Rasool, CH Siar, KP Ng. Oral Candida Species among
smokers and non-smokers. JCPSP 2005; 15(1): 679-682. (ISI-Cited Publication)
Kaw Bing Chua, Shamala Devi, Kee Peng Ng, Poh Sim
Hooi, Shiang Ling NA & Kerk Hsiang Chua. Negative
cross-reactivity of rabbit anti-Malassezia furfur
antibodies with other yeasts. Malaysian J Pathol
2005; 27(2): 123-125 (ISI-Cited Publication)
ST Tay, HC Chai, SL Na, KP Ng, TS Soo-Hoo Molecular
subtyping of clinical isolates of Candida albicans in
Malaysia. Mycopathologia 2005; 159 (3): 325-329. (ISI-Cited Publication)
| 2004 |
SD Puthucheary, KP NG, Hamimah H, A Hafeez, NS Raja:
Salmonellosis in patients infected with HIV: A report
of seven cases from Malaysia
SE Asian Journal of Tropical Medicine,2004;Vol 35
(2) : 1-5 (SCOPUS-Cited Publication)
Tee Kok-Keng, Pon Chee-Keong, Adeeba Kamarulzaman, Ng
Kee-Peng Emergence of HIV-1 CRF01_AE/B Unique
recombinant Forms in Kuala Lumpur, Malaysia. AIDS.
2004; 19:119-126. (ISI-Cited Publication)
Cheang, PY, Chong PP, Seow, HF, Mariana, NS, Ng, KP.
Cloning of Partial Sequences of the Phospholipase B
Gene homologues and characterization of phospholipase
activity in Medically important Candida species.
Abstracts of the Malaysian Society for Molecular
Biology and Biotechnology July 2004. Page 51 (ISI-Cited Publication)
Yip, MK, Chieng, DCS, Wong, WF, Badrulzaman,S, Ng, KP,
Seow, HF, Chong, PP. Detection of Systemic Candidemia
in Immunocompromised Patients using Real-Time PCR.
Abstracts of the Malaysian Society for Molecular
Biology and Biotechnology July 2004. Page 46. (ISI-Cited Publication)
| 2003 |
KP Ng, SL Na, TS Soo-Hoo and HT Lian, "Sepedonium species: an emerging opportunistic infection in a patient with AIDS", 2003, Vol. 25, no. 3, pg. 20-22,
GG Gan, JV Sangkar, KP Ng, TS Soo-Hoo, SL Na.
Disseminated Curvularia Lunata infection in a leukemia
patient: case report. J Infect Antimicrob Agents 2003;
20(3):151-154. (ISI-Cited Publication)
Looi,CY, Kwan, CL, Chong PP, Ng KP and Seow HF.
Comparison of CDR1 and MDR1 Gene Expression and Gene
sequences of Azole-drug Resistant Candida albicans and
Candida glabrata Clinical Isolates. Proceedings of the
28th Annual Conference of the Malaysian Society for
Biochemistry and Molecular Biology, 2003 page 82 (ISI-Cited Publication)
K P Ng, TS Soo-Hoo, S L Na, G G Gan, J V Sangkar.
Scopulariopsis brevicaulis infection in a patient with
acute myeloid leukemia. Med J Malaysia 2003; 58(4):608-
612. (ISI-Cited Publication)
Pei Pei Chong, Yee Lean Lee, Boon Chong Tan and Kee
Peng Ng. Genetic relatedness of Candida strains
isolated from women with vaginal candidiases in
Malaysia. J Med Microbiol 2003; 52:657-666. (ISI-Cited Publication)
KP Ng, TL Saw, A Baki & R Kamarudin. Evaluation of 3
commercial rapid tests for detecting antibodies to
human immunodeficiency virus. Med J Malaysia 2003;58
(3): 454-460. (ISI-Cited Publication)
Ghazali, K B Chua, K P Ng An Outbreak of Acute
Haemorrhagic Conjunctivitis in Melaka, Malaysia.
Singapore Med J 2003; 44(10): 511-516. (ISI-Cited Publication)
| 2002 |
Gan G G, Kamarulzaman A, Goh KY, Ng KP, Na SL, Soo-Hoo
TS. 2002. Non-sporulating Chrysosporium: An
opportunistic fungal infection in a neutropenic
patient. Med J Malaysia ;57(1) : 118-122 (SCOPUS-Cited Publication)
Ngeow Yung Fong, Ng Kee Peng, Savithiri Devi
Puthucheary, Lam Sai Kit. Health problems of foreign
workers Microbiological investigations. JUMMEC 2002;
7(1): 67-69 (ISI-Cited Publication)
| 2001 |
KP Ng, SL Na & TS Soo-Hoo. Dermatophytes isolated
from patients in University Hospital, Kuala Lumpur,
Malaysia. Mycopathologia 2001; 155:203-206. (ISI-Cited Publication)
Lee W S & K P Ng Seroprevalence of anti-HCV in an
urban child population: A preliminary study from Kuala
Lumpur. Singapore Med J 2001; 42(3):100-101. (ISI-Cited Publication)
| 2000 |
TS Saraswathy, KP Ng, M Sinniah Human Immunodeficiency
Virus Type 1 subtypes among Malaysian intravenous drug
users. Southeast Asian J Trop Med Public Health 2000;
31(2):152-158. (ISI-Cited Publication)
K P Ng, T L Saw, A Baki, J He, N Singh, CM Lyles . A
seroprevalence study of viral hepatitis E infection in
Human Immunodeficiency Virus type 1 infected patients
in Malaysia. Med J Malaysia 2000; 55(1):58-64. (ISI-Cited Publication)
| 1999 |
K P Ng, T L Saw, T S Soo-Hoo Systemic Candida
infection in University Hospital 1997-1999: the
distribution of Candida biotypes and antifungal
susceptibility patterns. Mycopathologia 1999; 148:141-
146 (ISI-Cited Publication)
TS Saraswathy, KP Ng, M Sinniah Diversity of envelope
V3 domain of HIV-1 subtype B. Int Med Res J l999; 3
(2): 89-93. (ISI-Cited Publication)
K.P Ng, M Madasamy, T L Saw, A Baki, J He, T S Soo-Hoo
Onychomycosis. Mycopathologica 1999; 147: 29-32. (ISI-Cited Publication)
K P Ng, M Madasamy, T L Saw, A Baki, J He, T S Soo-Hoo
Candida biotypes isolated from clinical specimens in
Malaysia. Mycopathologia 1999; 144: 135-140 (ISI-Cited Publication)
K P Ng, T L Saw. Hepatitis B surface antigen subtypes
in hepatitis B carriers. Med J Malaysia 1999; 54(3):
352-357. (ISI-Cited Publication)
K P Ng. T L Saw, A. Baki, J He, N Singh, C M Lyles.
Evaluation of a rapid test for the detection of
antibodies to human immunodeficiency virus type 1 and
2. Int J STD AIDS 1999; 10: 401-404. (ISI-Cited Publication)
| 1998 |
Lam SK, K P Ng. Public Health aspects of hepatitis B
in Malaysia. In hepatitis B in the Asian-Pacific
Region. Vol 2. Chronic hepatitis B prevention
strategies. Edited by A Zuckerman. Royal College of
Physicians. 1998. Page 127-128. (ISI-Cited Publication)
Lam SK, KP Ng. The contribution of migrant workers
to; hepatitis B transmission. In Hepatitis B in the
Asian-Pacific Region. Vol 2. Chronic hepatitis B
prevention strategies. Edited by A Zuckermanm. Royal
College of Physicians 1998. Page 83-85. (ISI-Cited Publication)
Lam SK, K P Ng. Prevention of hepatitis B transmission
in Malaysia. In Hepatitis B in the Asian-Pacific
Region. Vol 2. Chronic hepatitis B prevention
strategies. Edited by A Zuckerman. Royal College of
Physicians 1998. Page 57-59. (ISI-Cited Publication)
K P Ng, T L Saw, A Baki, Jun He, C M Lyles. Viral
hepatitis infections in HIV-1 infected patients in
Malaysia. Med J Malaysia 1998; 53(1): 1-13 . (ISI-Cited Publication)
Chris Beyrer, Thomas C Vancott, Ng Kee Peng, Andrew
Artenstein, G Duriasamy, M Nagaratnam, T L Saw Kenrad
E Nelson. HIV type I subtypes in Malaysia, determined
with serologic Assay 1992-1996. AIDS Res Hum
Retroviruses 1998; 4(18): 1687-1691. (ISI-Cited Publication)
| 1996 |
SK Lam, KP Ng, YF Ngeow. Screening and accuracy of HIV
testing. In : Proceedings of the workshop on the
epidemiology of HIV and AIDS: Methods, Approaches and
Application. Edited by SK Lam, KP Ng & YF Ngeow. Kuala
Lumpur, Malaysia. May 21-23, 1996. Page 51-58. (ISI-Cited Publication)
Yasim M Y, Ngeow Y F, K P Ng. Prevalence of Mycoplasma
Pneumoniae antibodies among Malaysians. Med J Malaysia
1996; 51(3): 328-331. (ISI-Cited Publication)
| 1995 |
K P Ng, T L Saw, Wong NWD, Chuah SY, Nagaratnam. The
prevalence of anti-HCV antibody in risk groups and
blood donors. Med J Malaysia 1995; 50(4):302-305 (ISI-Cited Publication)
K P Ng, M Bhanumathy, G S Y Ong, B H Yong, N
Parasakthi, M T Koh, C P Siow, J Bosco. Endotoxin
tests in patients with sepsis. J Endotoxin Res. 1995;
2:387-393 (ISI-Cited Publication)
D Rylatt, K Wilson, B E Kemp, MJ Elms, B
Manickavasagam, W Shi, A Cox, M J McArthur, K P Ng, G
Ong, C J Hillyard. A rapid test for endotoxin in whole
blood. In bacterial Endotoxins: Lipopolysaccharides.
Wiley-Liss, Inc. 1995; 273-284. (ISI-Cited Publication)
Rokiah I, K P Ng, T S Soo-Hoo. Penicillium marneffei
infection in an AIDS patient. Med J Malaysia 1995; 50
(1): 101-104. (ISI-Cited Publication)
| 1994 |
Ch ng S L, K P Ng. Diagnosis of hepatitis by
radioimmunoassay. Country report of RAS 6/10, November
1994 (ISI-Cited Publication)
K P Ng, K C Shekhar. The prevalence of
Cryptosporidiosis in children and adults at University
Hospital, Kuala Lumpur. Med J Malaysia 1994; 48(3):293-
296 (ISI-Cited Publication)
K C Shekhar, K P Ng. Human Isosporiasis in and AIDS
patient - Report of first case in Malaysia. Med J
Malaysia 1994; 48 (3):355-360 (ISI-Cited Publication)
K P Ng, T L Saw. Concurrence of Hepatitis B surface
antigen and antibodies in acute and chronic hepatitis
cases. Med J Malaysia 1994; 19 (2):117-121 (ISI-Cited Publication)
Ng Kee Peng, K C Shekhar. Cryptosporidium-like
organism from immunocompromised patients with
diarrhoea. Trop Biomed 1994; 11:111-113 (ISI-Cited Publication)
Ng Kee Peng, Rahman B Ismail, Saw Teik Leong.
Evaluation of a rapid whole blood test for antibodies
to HIV-1 and HIV-2. Asia Pacific J Mol Biol & Biotech
1994; 2(3):217-220 (ISI-Cited Publication)
K P Ng, T S Soo-Hoo, M T Koh, P W Kwan. Disseminated
Geotrichum Infection. Med J Malaysia 1994; 49(4):424-
426 (ISI-Cited Publication)
(Project title), (Role), (From)-(Until), (Source), (Level).
1. Title; A study on the immuno diagnosis of systemic candidiasis, Source and Amount of Financial Assistance; IRPA RM201,696, Dates; 1997-99, Co-researcher; Prof. J. Bosco (Jab. Perubatan), Prof. Gracie Ong, (Jab. Anaesthesiologi), Dr. Peter Bundasun (Agen BioMedial, Australia), Dr. Soo-Hoo Tuck Soon (Jab. Mikrobiologi Perubatan), Research results; - established laboratory protocol for identification of Candida species, - Two papers were published, the work developed to major grant MOSTE/BIOTEK Topdown Projects, (06-02-04-005BTK/023), 2008,
1. Title; To study the health of transsexual prostitutes in Kuala Lumpur, Source and Amount of Financial Assistance; F Vote, RM 6300.00, Dates; 1997/98, Co-researcher; Assoc. Prof. Eddie Teoh, Faculty of Science, Research result; High prevalence of HIV infections among transsexual prostitutes in Kuala Lumpur, Chromosomal abnormality was not detected within the transsexual, 2008,
2. Title; A study on the human immunodeficiency virus, Source and Amount of Financial Assistance; IRPA RM236,000, Dates; 1998 2000, Co-researcher ; Non, Research results; - molecular epidemiology of HIV genotypes in Malaysia, - developed HIV viral quantitative assay, the basis of HIV viral loads, - three research papers were published, the work developed to IRPA grant 36-02-03-6036 and CMB 103-00000-8122221, 2008,
2. Title; Laboratory studies of Mycotoxins produced by Fuserium species
Source and Amount of Financial Assistance; IRPA 06-02-03-0247-EA247, Rm 98,500.00, Dates; 2004 for 3 years, Co-researcher; Assoc Prof Dr H Hamimah, Objective; - to isolate, identify and characterize Fusarium species from the patients, environment and food samples, - to identify mycotoxin producing Fusarium isolates, - laboratory study of biological action of Fusarium mycotoxin, - to develop an immunoassay kit for the rapid detection of Fusarium mycotoxin, 2008,
3. Title; The use of Real Time PCR testing for the detection of HVB, HCV and HIV genome in blood donation, Source and Amount of Financial Assistance; CMB 103-00000-8122221. Rm 12000.00, Dates; 2003, Co-researcher; Mr Tee Kok Kheng (RA), Mr Pon Chee Keong (RA). Research results The main objective is to validate and evaluate the suitability of PCR in detecting HBsAg, HCV and HIV genomes in blood donors. RNA and DNA of 1872 blood samples were abstracted by Qiagen Ultrasen kit, amplified by ATS HIV, HBV and HCV RG Quantitative reagents and detected by Rotorgen. The data indicated that PCR did not enhance sensitivity in HBV, HCV and HIV screening compared to conventional MEIA. The main criticism of the project was the number of blood samples used in the study; the preliminary study suggested the needs of future NAT in blood transfusion services, 2008,
4. Title; Development of a genotypic assay for drug resistance HIV mutants and their impacts on management and control of HIV infections, Source and Amount of Financial Assistance; IRPA Rm 188,000.00, Dates; 2003-2005, Co-researcher ; Prof Adeeba (Department of Medicine), clinical component of the project. Objective; - To develop molecular genotypic assay to study the emergence of HIV- 1 drug resistant mutants, - To identify the nucleotide sequences of mutants and quasispecies of HIV-1, - To study the effects of the emergence of HIV drug resistant mutants on the clinical managemnt and control of HIV infection in Malaysia, 2008,
5. Title ; International Collaborative Study on Epidemiological Survey of HIV infections, isolation and Characterization of Unique HIV-1 Recombinants Emerging in Malaysia, Awarding agency; Japan Foundation for AIDS Prevention (JFAP), Amount; 6 juta Yen (USD 50,000), Principle Investigator; Professor Dr Adeeba Kamarulzaman, Department of Medicine, Faculty of Medicine, University of Malaya, Co-investigator; Prof. Dr Ng Kee Peng, 2008,
HIV; Molecular and genomic of HIV, bioinformatic approaches in studying the impacts of mutants on HIV infections in Malaysia, Research on HIV, 2008,
IMPACT OF HEPATITIS B MUTANTS ON THE CONTROL OF HEPATITIS B INFECTIONS IN THE ERA OF EXPANDED PROGRAM OF IMMUNIZATION, Principal Investigator(PI), 15/09/2008, , 14/09/2009
Mycology; morphologic and genomic approaches in fungal identification, Principal Investigator(PI), 2008,
PROTEOMIC APPROACHES TO STUDY THE BIOMAKERS FOR HIV DISEASE PROGRESSION AND NON-PROGRESSION AND DEVELOP NOVEL TECHNOLOGIES FOR RAPID AND SENSITIVE HIV DIAGNOSIS, Principal Investigator(PI), 01/12/2006, , 30/11/2008
PROTEOMIC APPROACHES TO STUDY THE BIOMARKERS FOR HIV DISEASE PROGRESSION AND NON-PROGRESSION AND DEVELOP NOVEL TECHNOLOGIES FOR RAPID AND SENSITIVE HIV DIAGNOSIS, Principal Investigator(PI), 01/06/2009, , 31/05/2010
Surveillance and screening of blood borne pathogensserology approaches, genomic amplification technologies, Viral Hepatitis, Hepatitis B, Impacts of HBV vaccination (EPI) on HBV infections in Malaysia, The project was initiated in 1997 collaborated with the Cancer Society of Malaysia (perak branch). Emergence of HBV mutants in Malaysia. Molecular epidemiology of HBV infections in Malaysia, Hepatitis C, Molecular epidemiology of HCV in Malaysia. HIV, HBV and HCV coinfections; impacts on HIV disease progression. Nucleic acid-amplification testing of HBV and HCV in blood donations. GBV, Molecular epidemiology of GBV in Malaysia. GBV and HIV disease progression, Principal Investigator(PI), 2008,
Title; Antifungal susceptibility Testing and DNA fingerprinting as molecular markers of Candida - applications for rapid diagnosis of systemic candidiasis, Source and Amount of Financial Assistance; MOSTE/BIOTEK Topdown Projects, (06-02-04-005BTK/023), RM 435, 000, Dates; Commence year 2003 for 3 years, Subproject leader; Dr. Ng Kee Peng, Co-Investigator; Dr. Chong Pei Pei, Objective; to assess the in vitro antifungal drug susceptibilities of clinical isolates of Candida from immunocompromised patients, to identify prevalence of antifungal drug resistance among Candida isolated, to perform genetic fingerprinting of Candida isolates by Random Amplified Polymorphic DNA analysis (RAPD), Principal Investigator(PI), 2008,
Title; Development of DNA-based Diagnostic Tool for detection of Azole-resistant Candida isolates, Source and Amount of Financial Assistance; MOSTE/IRPA RM 8, 06-02-04-0598-EA001, RM 217, 400, Dates; Commence year 2002 for 3 years, Co-researcher; Project Leader ; Dr. Chong Pei Pei, Co-Investigator; Dr K P Ng, Objective; To study the molecular basis of Azole-resistant Candida isolates, The impact of emergence of Azole-resistant Candida isolates on the management of patients, To develop a DNA-based diagnostic assay for identifying Azole-resistant Candida species, Principal Investigator(PI), 2008,
Title; Molecular Pathogenesis Study of Candida Infection; Towards Development of Novel Markers for Rapid Detection, Source and Amount of Financial Assistance; MOSTE/BIOTEK Topdown Projects, Total RM 2.17 million for whole project; RM 494, 000 for this subproject, Dates; Commence year 2003 for 3 years, Subproject leader; Dr. Chong Pei Pei, Co-Investigator; Dr Ng Kee Peng, Objective; to study pathogenesis of Candida infections, identification and characterization of proteins associated with pathogenesis, development of novel markers for detection of systemic Candida infections, Principal Investigator(PI), 2008,