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CURRICULUM VITAE
PERSONAL DETAILS

Name
  Prof. Dr. Onn Bin Haji Hashim
Designation
  Professor
Department
  Department of Molecular Medicine
Faculty
  Faculty of Medicine
Tel. No. (Office)
  79674906
Fax No.
  79674957
E-mail Address
  onnhashim@um.edu.my
ResearcherID Link
  http://www.researcherid.com/rid/B-9459-2010
Address(Office)
  Department of Molecular Medicine, Faculty of Medicine University of Malaya, 50603 Kuala Lumpur, MALAYSIA

ACADEMIC QUALIFICATION
(Qualification), (Institution).
PHD, UNIVERSITY OF GLASGOW, SCOTLAND
BSC, UNIVERSITY OF MALAYA (UM)

PROFESSIONAL AFFILIATION/MEMBERSHIP
(Organisation), (Role), (Year), (Level).

Malaysian Society for Biochemistry and Molecular Biology, Elected Council Member, 2003-2005, (National)

ADMINISTRATIVE DUTIES
(Role), (Level), (Start date),(End Date).


Panel member, Health and Translational Medicine Research Cluster., University Malaya, 01-Jan-11 - 31-Dec-12

Panel member, Biotechnology and Bioproduct Research Cluster., University Malaya, 01-Jan-11 - 31-Dec-12

Panel member, Advance Fundamental Research Cluster., University Malaya, 01-Jan-11 - 31-Dec-12

Health and Translational Medicine Research Cluster, Board of Advisor., University Malaya, 01-Jan-10

Member, Panel for Renewal of Contract for Research Officer, University of Malaya., University Malaya, 16-Dec-09

Member, Faculty of Medicine Conference Committee., Faculty Of Medicine, 11-Oct-09 - 10-Oct-12

Biotechnology & Bioproduct Research Cluster, University of Malaya, Panel Member., University Malaya, 01-Jan-09 - 31-Dec-10

Member (Alternate), Selection Committee of Post-Doctoral Research Fellow., University Malaya, 02-Jan-08

Chairman of Ad-Hoc Committees to evaluate applications for PhD candidature., Faculty Of Medicine, 01-Jan-08

Member, Short-term Research Funding (PJP) Committee (Research University Special Grant)., University Malaya, 01-Jan-08 - 31-Dec-09

Member, Faculty of Medicine Conference Committee., Faculty Of Medicine, 11-Oct-06 - 10-Oct-09

Head Of Department, Department Of Molecular Medicine, Faculty Of Medicine, 01-Jan-06 - 31-Aug-09

Proteomics Advisor, Medical Biotechnology Laboratory. , Faculty Of Medicine, 01-Jan-06 - 31-Dec-08

Member, Faculty of Medicine Undergraduate Intake Committee., Faculty Of Medicine, 01-Jan-06 - 31-Dec-08

Phase I MBBS Course Coordinator., Faculty Of Medicine, 01-Jan-04 - 31-Dec-04

Medical Biochemistry Programme Coordinator for the MBBS course., Faculty Of Medicine, 01-Jan-03 - 31-Dec-03

Pharmaceutical Biochemistry Programme Coordinator for the BPharm course., Department Of Molecular Medicine, Faculty Of Medicine, 01-Jan-00 - 31-Dec-02

AREAS OF EXPERTISE
(Area).

Human Serum Glycoproteins

Plant Lectins

Proteomics Technology

RECENT SELECTED PUBLICATIONS
(Publication).
 
Book
 
2003

Onn Hashim (2003) Metabolisme tubuh manusia (Human body metabolism) (2nd edition), UM Press, Kuala Lumpur, 327pp (ISBN 983-100-168-0). (Non-ISI/Non-SCOPUS Cited Publication)
 
2000

Onn Hashim (2000) Metabolisme tubuh manusia (Human body metabolism) (1st edition), UM Press, Kuala Lumpur, 275pp (ISBN 983-100-088-9). (Non-ISI/Non-SCOPUS Cited Publication)
 
Chapter In Book
 
1995

Mestecky, J., Hashim, O.H. and Tomana, M. (1995) Alterations in the IgA carbohydrate chains influence the cellular distribution of IgA1. In Clarkson AR, Woodroffe AJ (eds): IgA Nephropathy: Pathogenesis and Treatment. Karger Basel., Contribution to Nephrology, 111, 66-71 (ISBN 3-8055-6030-3). (ISI-Cited Publication)
 
Article In Academic Journals
 
2012

Vellasamy, K.M., Mariappan, V., Hashim, O.H. and Vadivelu, J. (2012) Functions of Burkholderia virulence factors: Input from proteomics and DNA microarray analyses. Journal of Analytical Science and Technology, 3:72-80. 

Chan, H. H., Rahim, Z.H.A., Jessie, K., Hashim, O.H. and Taiyeb-ali T. B. (2012) Salivary proteins associated with periodontitis in patients with Type 2 diabetes mellitus. International Journal of Molecular Sciences, 13, 4642-4654. (ISI-Cited Publication)

Jayapalan, J. J., Ng, K. L., Razack, A. H. A. and Hashim, O. H. (2012) Identification of potential complementary serum biomarkers to differentiate prostate cancer from benign prostatic hyperplasia using gel- and lectin-based proteomics analyses. Electrophoresis, 33, 1855-1862. (ISI-Cited Publication)

Aminudin N, Abdullah NAH, Misbah H, Karsani SA, Husain R, Hoe SZ and Hashim OH. 2012. Treatment with captopril abrogates the altered expression of alpha1 macroglobulin and alpha1 antiproteinase in sera of spontaneously hypertensive rats. Proteome Science. 2012, 10:17 doi:10.1186/1477-5956-10-17 (ISI/SCOPUS Cited Publication)

Chong URW, Abdul-Rahman PS, Abdul-Aziz A, Hashim OH, Mat-Junit S.2012. Tamarindus indica Extract Alters Release of Alpha Enolase, Apolipoprotein A-I, Transthyretin and Rab GDP Dissociation Inhibitor Beta from HepG2 Cells. PLOS ONE, 7(6): e39476. (ISI-Cited Publication)

Mu, A.K.W., Lim, B.K., Hashim, O.H. and Shuib, A.S. (2012) Detection of differential levels of proteins in the urine of patients with endometrial cancer: analysis using two-dimensional gel electrophoresis and O-glycan binding lectin. International Journal of Molecular Sciences, 13, 9489-9501. (ISI-Cited Publication)
 
2011

Mariappan, V., Vellasamy, K.M., Hashim, O.H. and Vadivelu, J. (2011) Profiling of Burkholderia cepacia secretome at mid-logarithmic and early-stationary phases of growth. PLoS ONE 6(10): e26518. doi:10.1371/journal.pone.0026518. (ISI-Cited Publication)

Golbabapour, S., Pang, W.W., George, J., Pasupati, T., Abdul-Rahman, P.S. and Hashim, O.H. (2011) Chemically induced breast tumors in rats are detectable in early stages by contrast enhanced magnetic resonance imaging but not by changes in the acute-phase reactants in serum. International Journal of Molecular Sciences, 12, 1030-1040. (ISI-Cited Publication)
Golbabapour et al.pdf

Vellasamy, K.M., Mariappan, V., Hashim, O.H. and Vadivelu, J. (2011) Identification of immunoreactive secretory proteins from the stationary phase culture of Burkholderia pseudomallei. Electrophoresis, 32, 310- 320. (ISI-Cited Publication)
Vellasamy et al.pdf
 
2010

Pang, W.W., Abdul-Rahman, P.S., Wan-Ibrahim, W.I. and Hashim, O.H. (2010) Can the acute-phase reactant proteins be used as cancer biomarkers? International Journal of Biological Markers, 25, 1-11. (ISI-Cited Publication)
pang et al.pdf

Mariappan, V., Vellasamy, K.M., Thimma, J.S., Hashim, O.H. and Vadivelu, J. (2010) Identification of immunogenic proteins from Burkholderia cepacia secretome using proteomic analysis. Vaccine, 28, 1318- 1324. (ISI-Cited Publication)
mariappan et al.pdf

Gabrielsen, M., Abdul-Rahman, P.S., Isaacs, N.W., Hashim, O.H. and Cogdell, R.J. (2010) Crystallization and initial X-ray diffraction analysis of a mannose- binding lectin from Champedak. Acta Crystallographica F, 66, 592-594. (ISI-Cited Publication)
Gabrielsen et al.pdf

Seriramalu, R., Pang, W. W., Jayapalan, J. J., Mohamed, E., Abdul-Rahman, P. S., Bustam, A. Z., Khoo, A. S. B. and Hashim, O. H. (2010) Application of champedak mannose binding lectin in the glycoproteomic profiling of serum samples unmasks reduced expression of alpha-2 macroglobulin and complement factor B in patients with nasopharyngeal carcinoma. Electrophoresis, 31, 2388-2395. (ISI-Cited Publication)
seriramalu et al.pdf

Jessie, K., Pang, W.W., Rahim, Z.H.A. and Hashim, O.H. (2010) Proteomic analysis of whole human saliva detects enhanced expression of interleukin-1 receptor antagonist, thioredoxin and lipocalin-1 in cigarette smokers compared to non-smokers, International Journal of Molecular Sciences, 11, 4488-4505. (ISI-Cited Publication)
Jessie et al.pdf

Abdullah-Soheimi, S.S., Lim, B.K., Hashim, O.H. and Shuib, A.S. (2010) Patients with ovarian carcinoma excrete different altered levels of urine CD59, kininogen-1 and fragments of inter-alpha-trypsin inhibitor heavy chain H4 and albumin. Proteome Science, 8:58 (doi:10.1186/1477-5956-8-58). (ISI-Cited Publication)
Abdullah-Soheimi et al.pdf
 
2009

Chen, Y., Lim, B.K. and Hashim, O.H. (2009) Stage correlative expression of high abundance acute-phase proteins in sera of patients with epithelial ovarian carcinoma. Journal of Hematology and Oncology, 2, 37 (doi:10.1186/1756-8722-2-37) (ISI-Cited Publication)

Gabrielsen, M., Riboldi-Tunicliffe, A., Abdul-Rahman, P.S., Mohamed, E., Ibrahim, W.I.W., Hashim, O.H., Isaacs, N.W. and Cogdell, R.J. (2009) Crystallization and preliminary structural studies of Champedak galactose-binding lectin, Acta Crystallographica F, 65, 895-897. (ISI-Cited Publication)
 
2008

Chen, Y., Lim, B.K., Peh, S.C., Abdul-Rahman, P.S. and Hashim, O.H. (2008) Profiling of serum and tissue high abundance acute-phase proteins of patients with epithelial and germ line ovarian carcinoma. Proteome Science, 6, 20. (ISI-Cited Publication)

Jessie, K., Hashim, O.H. and Rahim, Z.H.A. (2008) Precipitation methods for salivary proteins and rehydration buffer for two-dimensional electrophoresis, Biotechnology, 7(4), 686-693. 

Mohamed, E., Abdul-Rahman, P.S., Doustjalali, S.R., Chen, Y., Lim, B.K., Omar, S.Z., Bustam, A.Z., Singh, V.A., Muhammad-Taib, N.A., Yip, C.H. and Hashim, O.H. (2008) Lectin-based electrophoretic analysis of the expression of the 35 kDa inter-alpha-trypsin inhibitor heavy chain H4 fragment in sera of patients with five different malignancies. Electrophoresis, 29, 2645- 2650. (ISI-Cited Publication)
 
2007

Abdul-Rahman, P.S., Lim, B.K. and Hashim, O.H. (2007) Expression of high abundance proteins in sera of patients with endometrial and cervical cancers: analysis using two-dimensional gel electrophoresis with silver staining and lectin detection methods, Electrophoresis, 28, 1989-1996. (ISI-Cited Publication)

Hashim, O. H. (2007) Overview of proteomics (a review), Malaysian Journal of Biochemistry and Molecular Biology, 15, 1-7. (Non-ISI/Non-SCOPUS Cited Publication)
 
2006

Muliawan S.Y., Lam, S.K., Devi, S., Hashim, O.H. and Yusof, R. (2006) Inhibitory potential of Quercus lusitanica extract on dengue virus type 2 replication, Southeast Asian Journal of Tropical Medicine and Public Health, 37, 132-135. (SCOPUS-Cited Publication)

Yong, P.H., Mat Junit, S., Harun, F. and Hashim, O.H. (2006) Patients with congenital hypothyroidism demonstrate different altered expression of plasma fibrinogen and haptoglobin polypeptide chains, Clinical Biochemistry, 39, 126-132. (ISI-Cited Publication)

Doustjalali, S.R., Yusof, R., Govindasamy, G.K., Bustam, A.Z., Pillay, B. and Hashim, O.H. (2006) Patients with nasopharyngeal carcinoma demonstrate enhanced serum and tissue ceruloplasmin expression, Journal of Medical Investigation, 53, 20-28. (ISI/SCOPUS Cited Publication)
 
2004

Doustjalali, S.R., Yusof, R., Yip, C.H., Looi, L.M., Pillay B. and Hashim, O.H. (2004) Aberrant expression of acute-phase reactant proteins in sera and breast lesions from patients with malignant and benign breast tumours, Electrophoresis, 25, 2392-2401. (ISI-Cited Publication)
 
2002

Abdul Rahman, M., Karsani, S.A., Othman, I., Abdul Rahman, P.S. and Hashim, O.H. (2002) Galactose binding lectin from the seeds of champedak (Artocarpus integer): sequences of its subunits and interactions with human serum O-glycosylated glycoproteins, Biochemical and Biophysical Research Communications. 295, 1007-1013. (ISI-Cited Publication)
 
2001

Hashim, O.H., Ahmad, F. and Shuib, A.S. (2001) The application of Artocarpus integer seed lectin-M in the detection and isolation of selective serum acute-phase proteins and immunoglobulins, Immunological Investigations, 30, 131-141. (ISI-Cited Publication)

Hashim, O.H., Shuib, A.S. and Chua, C.T. (2001) Neuraminidase treatment abrogates the binding abnormality of IgA1 from IgA nephropathy patients and the differential charge distribution of its alpha-heavy chains, Nephron, 89, 422-425. (ISI-Cited Publication)

Hashim, O.H., Shuib, A.S. and Chua, C.T. (2001) The interaction of selective plant lectins with neuraminidase-treated and untreated IgA1 from the sera of IgA nephropathy patients, Immunological Investigations, 30, 21-31. (ISI-Cited Publication)

Hashim, O.H. and Shuib, A.S. (2001) Champedak and jackfruit galactose-reactive lectins demonstrated minor preferential binding to electrophoresed alpha-heavy chains lacking in sialic acid residues, Malaysian Journal for Biochemistry and Molecular Biology, 6, 40-43. (Non-ISI/Non-SCOPUS Cited Publication)

Hashim, O.H. and Shuib, A.S. (2001). Champedak and jackfruit galactose-reactive lectins demonstrated minor preferential binding to electrophoresed alpha-heavy chains lacking in sialic acid residues. Mal. J. Biochem. Mol. Biol. 6. 40-43. 
 
1998

Lim, S.B., Kanthimathi, M.S. and Hashim, O.H. (1998) Effect of the mannose-binding Artocarpus integer lectin on the cellular proliferaton of murine lymphocytes. Immunological Investigations, 27, 395-404. (ISI-Cited Publication)

Shuib, A.S., Chua, C.T. and Hashim, O.H. (1998) Sera of IgA nephropathy patients contain a heterogeneous population of relatively cationic alpha heavy chains. Nephron, 78, 290-295. (ISI-Cited Publication)
 
1997

Lim, S.B., Chua, C.T. and Hashim, O.H. (1997) Isolation of a mannose-binding and IgE- and IgM-reactive lectin from the seeds of Artocarpus integer. Journal of Immunological Methods, 209, 177-186. (ISI-Cited Publication)
 
1994

Hashim, O.H., Gendeh, G.S., Cheong, C.N. and Nik Jaafar, M.I. (1994) Effect of Artocarpus integer lectin on functional activity of guinea-pig complement. Immunological Investigations, 23, 153-160. (ISI-Cited Publication)

Hashim, O.H. and Adnan, N.A. (1994) Coenzyme, cofactor and prosthetic group - ambiguous biochemical jargon. Biochemical Education, 22, 93-94. (ISI-Cited Publication)
 
1993

Hashim, O.H., Gendeh, G.S. and Nik Jaafar, M.I. (1993) Comparative analyses of IgA1 binding lectins from seeds of six distinct clones of Artocarpus integer. Biochemistry and Molecular Biology International, 29, 69-76. (ISI-Cited Publication)
 
1992

Hashim, O.H., Gendeh, G.S. and Nik Jaafar, M.I. (1992) Lectin extracts of champedak seeds demonstrate selective stimulation of T lymphocyte proliferation. Biochemistry International, 27, 139-143. (ISI-Cited Publication)

Hashim, O.H., Kobayashi, K. and Taniguchi, N. (1992) Interaction of Artocarpus lectins with human IgA does not involve asparagine-linked oligosaccharide of the immunoglobulin. Biochemistry International, 27, 423-429. (ISI-Cited Publication)
 
1991

Hashim, O.H., Ng, C.L., Gendeh, G.S. and Nik Jaafar, M.I. (1991) IgA binding lectins from distinct Artocarpus species demonstrate differential specificity. Molecular Immunology, 28, 393-398. (ISI-Cited Publication)

Hashim, O.H. (1991) The ELISA test (a video review). Biochemical Education, 19, 38. (ISI-Cited Publication)

Hashim, O.H. and Hassan, H. (1991) Actions of three Clostridial IgA proteases on distinct forms of immunoglobulin A molecules. Immunology, 73, 235-238. (ISI-Cited Publication)
 
1988

Hashim, O.H. and Cushley, W. (1988) Simultaneous inhibition of multiple steps in the processing of N-linked oligosaccharides does not impair immunoglobulin secretion from rat hybridoma cells. Immunology, 63, 383-388. (ISI-Cited Publication)
 
1987

Hashim, O.H. and Cushley, W. (1987) Minor modifications to the structure of Tunicamycin lead to loss of the biological activity of the antibiotic. Biochimica et Biophysica Acta, 923, 362-370. (ISI-Cited Publication)

Hashim, O.H. and Cushley, W. (1987) Role of processing of N-linked oligosaccharides in control of immunoglobulin secretion from rat hybridomas. Molecular Immunology, 24, 1087-1096. (ISI-Cited Publication)
 
Proceeding
 
2010

Hashim, O.H. (2010) Cancer biomarkers from the proteome. 35th Ann. Conf. Mal. Soc. Biochem. Mol. Biol. Conf., Bangi, p23. 

Mu, A.K.W., Lim, B.K., Hashim, O.H. and Shuib, A.S. (2010) Glycoproteomic analysis of aberrantly glycosylated urinary proteins from endometrial cancer by lectin blotting. 35th Ann. Conf. Mal. Soc. Biochem. Mol. Biol. Conf., Bangi, p49. 

Doustjalali, S. R., Chen, Y., Abdul-Rahman, P. S., Mohamed, E., Seriramalu, R., Pang, W. W. and Hashim, O. H. (2010) Gel- and lectin-based serum proteomics profiling in search for new complementary biomarkers for cancer. National Biotechnology Conference, PWTC. 
 
2009

Hashim, O.H. (2009) Acute-phase protein response: can it be used as a diagnostic tool for cancer? PepCon2009, Seoul, p135. 

Mohamed, E., Abdul-Rahman, P.S., Omar,S.Z. and Hashim, O.H. (2009) Association of sex steroid hormone dysregulation with the over expression of serum 35 kDa inter alpha trypsin H4 fragment. 21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology, Shanghai. p217 

Wan-Ibrahim, W.I., Karsani, S.N., Hashim, O.H. and Abdul-Rahman, P.S. (2009) Establisment of serum O- glycoproteome using shot-gun-MS analysis. 34th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, and 3rd ASEAN Biochemistry Conference. 7-8 October 2009 Kuala Lumpur. p33 

Vanitha, M., Kumutha, M.V., Thimma, J., Hashim, O.H. and Vadivelu J. (2009) Comparison of immunogenic proteins by immunoproteome analysis of Burkholderia cepacia secretome. 10th APRU Doctoral Students Conference, Kyoto. 

Vanitha, M., Kumutha, M.V., Thimma J., Hashim, O.H. and Vadivelu, J. (2009) Immunoproteomic analysis of Burkholderia cepacia secretory proteins at different growth phase. The 14th Biological Sciences Graduate Congress. Chulalangkorn. 

Kumutha, M.V., Vanitha, M., Hashim, O.H. and Vadivelu, J.(2009) Proteome mapping and identification of Burkholderia pseudomallei secreted proteins. 14th Biological Sciences Graduate Congress. Chulalangkorn. 

Nga, D.C., Abdul-Rahman, P.S., Hashim, O.H. and Mimiwati, Z. (2009) Matrix Metalloproteinases and their inhibitor in aqueous humour of patients with open-angle glaucoma and primary angle-closure glaucoma. World Glaucoma Congress, Boston, p96. 

Abdul-Rahman, P.S., Mohamed, E., Singh, V.A. and Hashim, O.H. (2009) Patients with different bone cancers demonstrate distinctive altered expression of serum protein profiles. EMBO Cancer Proteomics, Dublin, p1. 
 
2008

Abdul-Rahman, P.S., Lim, B.K., Yunos, N.M., Adnan, M.I. and Hashim, O.H. (2008) SELDI-MS Profiling of O-glycosylated proteins in sera of patients with endometrial adenocarcinoma. FEBS Journal 275, 242. (ISI-Cited Publication)

Mohamed, E., Shanaz, A.R.P., Omar, S.Z., Abdul-Rahman, P.S. and Hashim, O.H. (2008) Lectin-generated serum O-glycosylated proteins in sera of patients with hydatidiform mole. FEBS Journal 275, 246. (ISI-Cited Publication)

Abd-Manap, M.N., Hashim, O.H., Zubairi Y.Z. and Yusoff, K.M. (2008) Anti-inflammatory effect of Malaysian bee venom. VI German Apitherapy and Acupuncture Congress, Passau. 

Abd-Manap, M.N., Hashim, O.H., Mohamed, E., Abdul-Rahman, P.S. and Yusoff, K.M. (2008) Discovery of bee venom bioactive components: a proteomic approach. VI German Apitherapy and Acupuncture Congress, Passau. 

Abd-Manap, M.N., Hashim, O.H., Mohamed, E., Abdul-Rahman, P.S. and Yusoff, K.M. (2008) Proteomic analysis of differentially expressed proteins in sera of carrageenan induced rats treated with Malaysian bee venom. VI German Apitherapy and Acupuncture Congress, Passau. 

Kumutha M.V. , Vanitha M., Thimma J., Hashim O. and Vadivelu J. (2008) Immunoproteomics analysis of Burkholderia pseudomallei secretome. 13th Biological Sciences Graduate Congress (BSGC), Singapore, p26. 

Vanitha, M. , Kumutha, M.V. , Thimma, J., Hashim O. and Vadivelu J. (2008) Comparison of immunogenic proteins by immunoproteome analysis of Burkholderia cepacia secretome. 13th Biological Sciences Graduate Congress (BSGC), Singapore, p28. 

Mohamed, E., Abdul-Rahman, P.S., Omar, S.Z. and Hashim, O.H. (2008) Overexpression of the 35kDa ITIH4 fragment: Exclusive to sex-steroid hormone associated cancer. Mal. J. Biochem. Mol. Biol. 17(1), 33. 

Seriramalu, R., Abdul-Rahman, P.S., Bustam, A.Z., Khoo, A. and Hashim, O.H. (2008) Two-dimensional gel electrophoretic profiling of low abundance serum proteins of patients with nasopharyngeal carcinoma WHO types 2 and 3. Mal. J. Biochem. Mol. Biol., 17 (1), 52. 

Soheimi, S.S., Lim, B.K., Omar, S.Z., Hashim, O.H. and Shuib, A.S. (2008) Two-dimensional gel electrophoretic analysis of urinary proteins of patients with ovarian carcinoma and cervical cancer. Mal. J. Biochem. Mol. Biol., 17(1), 99. 

Vanitha, M. , Kumutha, M.V. , Hashim O. and Vadivelu J. (2008) Identification of immunoreactive secretory antigens from Burkholderia cepacia against monoclonal antibody. International Journal of Infectious Diseases, 12: 227. (ISI-Cited Publication)

Kumutha M.V. , Vanitha M., Thimma J., Hashim O. and Vadivelu J. (2008) Invasion efficiency of Burkholderia pseudomallei from different clinical sources. International Journal of Infectious Diseases, 12: 228. (ISI-Cited Publication)

Abdul-Rahman, P.S., Yunos, N.M., Adnan, M.I., Lim, B.K. and Hashim, O.H. (2008) Profiling of O-glycosylated proteins in sera of patients with endometrial adenocarcinoma. Mal.J. Biochem. Mol. Biol., 16, 70. 

Kang, I.N., Musa, M., Yong, P.H., Mansor, S.F., Harun, F., Hashim, O.H. and Junit, S.M. (2008) Novel mutations and polymorphisms in thyroid-specific genes in patients with congenital hypothyroidism. Mal.J. Biochem. Mol. Biol., 16, 69. 

Rosli, S.N.Z., Hashim, O.H., Mohd-Zain, R., Hussaini, H.M., Abdul-Rahman, M., Zainal-Abidin, Z., and Karsani, S.A. (2008) Identification of differentially expressed proteins in the serum of oral cancer patients by two-dimensional electrophoresis. Mal.J. Biochem. Mol. Biol., 16, 67. 

Mohamed, E., Abdul-Rahman, P., Omar, S.Z. and Hashim, O.H. (2008) Serum two-dimensional electrophoretic profiles of patients with molar pregnancy. Mal.J. Biochem. Mol. Biol., 16, 62. 

Shuib, A.S., Murat, S.S.C., Sulaiman, S and Hashim, O.H. (2008) Development of CGB-lectin-based latex agglutination assay in detecting hCG. Mal.J. Biochem. Mol. Biol., 16, 51. 

Abdul-Manap, M.N., Mohd. Yusoff, K., Hashim, O.H. and Zubairi, Y.Z. (2008) Malaysian bee venom abrogates carrageenan-induced inflammatory effects in rats. Mal.J. Biochem. Mol. Biol., 16, 45. 

Che Murat, S.S., Hashim, O.H., Sulaiman, S. and Shuib, A.S. (2008) Interaction of the champedak galactose binding lectin with O-linked oligosaccharides of human chorionic gonadotropin. Mal. J. Biochem. Mol. Biol., 17 (1), 68. 
 
2007

Hashim, O.H. (2007) Proteomics and cancer. J. Health Management., p27. 

Rosli, S.N.Z., Hashim, O.H., Mohd-Zain, R, Mohd-Hussaini, H., Abdul-Rahman, M., Zainal-Abidin, Z. and Karsani, S.A. (2007) Identification of differentially expressed proteins in serum samples of oral cancer patients by two dimensional electrophoresis. 2nd Reg. Conf. Mol. Med., Kuala Lumpur, p52. 

Abdul-Rahman, P.S., Yunos, N.M., Adnan, M.I., Lim, B.K. and Hashim, O.H. (2007) Profiling of O-glycosylated proteins in sera of patients with endometrial adenocarcinoma using SELDI-MS. 32nd Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Petaling Jaya, p122. 

Kang, I.N., Musa, M., Yong, P.H., Mansor, S.F., Harun, F., Hashim, O.H. and Junit, S.M. (2007) Novel mutations and polymorphisms in thyroid-specific genes in patients with congenital hypothyroidism. 32nd Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Petaling Jaya, p119. 

Rosli, S.N.Z., Hashim, O.H., Mohd-Zain, R., Hussaini, H.M., Abdul-Rahman, M., Zainal-Abidin, Z., and Karsani, S.A. (2007) Identification of differentially expressed proteins in the serum of oral cancer patients by two-dimensional electrophoresis. 32nd Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Petaling Jaya, p113. 

Mohamed, E., Abdul-Rahman, P., Omar, S.Z. and Hashim, O.H. (2007) Serum two-dimensional electrophoretic profiles of patients with molar pregnancy. 32nd Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Petaling Jaya, p101. 

Shuib, A.S., Murat, S.S.C., Sulaiman, S and Hashim, O.H. (2007) Development of CGB-lectin-based latex agglutination assay in detecting hCG, 32nd Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Petaling Jaya, p67. 

Abdul-Manap, M.N., Mohd. Yusoff, K., Hashim, O.H. and Zubairi, Y.Z. (2007) Malaysian bee venom abrogates carrageenan-induced inflammatory effects in rats. 32nd Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Petaling Jaya, p48. 

Mariappan, V., Vellasamy, K.M., Suppiah, J., Thimma, J., Hashim, O.H. and Vadivelu, J. (2007) Identification of common immunodominant secretory antigens between Burkholderia cepacia and Burkholderia pseudomallei. 5th World Melioidosis Congress, Khon Kean, gep008. 

Abdul-Rahman P.S., Chen, Y, Doustjalali, S.R., Mohamed, E., Lim, B.K., Mohd-Taib, N.A., Yip, C.H. and Hashim, O.H. (2007) Profiling of O-glycosylated serum proteins of patients with cancer using the gel-based proteomics approach and lectin detection. Int. Symp. Glycoconjugate, Cairns, Glycoconj. J. 24, 334. (ISI-Cited Publication)
 
2006

Abdul Rahman, P.S., Lim, B.K. and Hashim, O.H. (2006) Serum proteomic profiling of patients with endometrial and cervical carcinomas. 31st Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Bangi, p57. 

Abdul Rahman, P.S., Lee, E.S., Hashim, O.H. and Shuib, A.S. (2006) Application of lectin-coated magnetic beads in the proteomic profiling of human serum glycoprotein. 31st Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Bangi, p58. 

Vellasamy, K.M., Mariappan, V., Vadivelu, J., and Hashim, O.H. (2006) Comparison of secretory protein profile of Burkholderia pseudomallei and Burkholderia thailandensis using two-dimensional gel electrophoresis. 16th Sci. Meet. Mal. Soc. Mol. Biol Biotech., Kuala Lumpur. 

Mariappan, V., Vellasamy, K.M., Vadivelu, J., and Hashim, O.H. (2006) Comparative proteome analysis of extracellular secreted protein from Burkholderia cepacia at different growth phase. 16th Sci. Meet. Mal. Soc. Mol. Biol Biotech., Kuala Lumpur. 
 
2005

Hashim, O.H. and Shuib, A.S. (2005) Lectin-based urinary hCG detection for confirmation of pregnancy. 3rd Nat. Biotech. Conf., New Delhi, p75. 

Hashim, O.H. (2005) Proteomics approach to cancer studies. 2nd Int. UM Res. Imaging Symp., Subang Jaya, p12. 

Shuib, A.S., Hashim, O.H., Sulaiman, S and Omar, S.Z. (2005) Urinary proteomics of molar disease, 15th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Kuala Lumpur, p17. 

Abdul Rahman, P.S., Lim, B.K., Mian, S., Rees, R. and Hashim, O.H. (2005) Application of lectin affinity chromatography and mass spectrometry for profiling of human serum glycoproteins. 15th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Kuala Lumpur, p17. 
 
2004

Doustjalali, S.R., Yusof, R., Govindasamy, G.K., Bustam, A.Z., Pillay, B. and Hashim, O.H. (2004) Potential role of caeruloplasmin as a novel biomarker for diagnosis and monitoring of nasopharyngeal carcinoma, Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Bangkok, p68. 

Abdullah, A., Lim, B.K., Hashim, O.H. and Yusof, R. (2004) HPV detection and biomarkers screening to monitor cervical cancer persistency, 14th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Malacca, p44. 

Chai, H.C., Tay, S.T., and Hashim, O.H. (2004) A preliminary study on the proteome of Cryptococcus neoformans and identification of immunogenic proteins, 14th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Malacca, p50. 

Chen, Y., Lim, B.K., and Hashim, O.H. (2004) Serum protein profiles of ovarian carcinoma patients, 14th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Malacca, p53. 

Hashim, O.H. (2004) Lectins from the seeds of champedak; from waste to wonders, 29th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p18-19. 

Chen, Y., Lim, B.K., and Hashim, O.H. (2004) Two dimensional serum protein profiles of patients with germ cell and epithelial ovarian carcinomas, 29th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p128. 

Kanthimathi, M.S., Chai, J.W., Lee, I.L., Kuppusamy, U.R., Wiart, C. and Hashim, O.H. (2004) Protein expression in cancer cells treated with selected plant extracts, 11th Ann. Meet Soc. for Free Radicals and Radioprotectors, India, p71. 
 
2003

Doustjalali, S.R., Yusof, R., Othman, I., Yip, C.H., Looi, L.M. and Hashim, O.H. (2003) Patients with breast disorders demonstrate aberrant two-dimensional electrophoretic serum protein expression maps, Int. Council Electro. Soc Conf, Glasgow, p41. 

Yong, P.H., Mat Junit, S., Harun, F. and Hashim, O.H. (2003) Patients with congenital hypothyroidism demonstrate differential expression of plasma fibrinogen and haptoglobin, 17th Asia Oceania Thyroid Assoc. Cong., Singapore, p63. 

Abdul Rahman, P.S., Shuib, A.S., Doustjalali, S.R., Lim, B.K., Othman, I. and Hashim, O.H. (2003) Profiling sera of patients with cervical carcinoma using proteomics technology, 28th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Putrajaya, p75. 

Doustjalali, S.R., Abdul Rahman, P.S., Shuib, A.S., Yusof, R., Othman, I., Yip, C.H., Looi, L.M. and Hashim, O.H. (2003) Lectin generated serum proteomes of patients with breast disorders, 28th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Putrajaya, p79. 

Muliawan, S.Y., Lam, S.K., Hashim, O.H. & Yusof R. (2003) Protein expression of dengue virus type 2 in two-dimensional gel electrophoresis, J Clin Virol, 28, S30. (ISI/SCOPUS Cited Publication)

Muliawan, S.Y., Lam, S.K., Hashim, O.H. & Yusof R. (2003) Proteomics Study on the inhibitory effect of Quercus lusitanica against dengue virus type-2, 28th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Putrajaya, p95. 
 
2002

Doustjalali, S.R., Yusof, R., Looi, L.M., Yip, C.H., Govindasamy, G.K., Bustam, A.Z., Othman, I., and Hashim, O.H. (2002) Sera of patients with breast and nasopharyngeal carcinomas demonstrate differential two-dimensional electrophoretic proteome maps, 12th Sci. Meet. Mal. Soc. Mol. Biol Biotech., p103. 

Abdul Rahman, P.S.A., Yeoh, K.H.C. and Hashim, O.H. (2002) Separation of human serum glycoproteins by sequential immobilised lectin and hemin affinity chromatography, 12th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Kuala Lumpur, p97. 

Yong, P.H., Mat Junit, S., Harun, F. and Hashim, O.H. (2002) Serum protein expression maps of patients with congenital hypothyroidism: a preliminary investigation, 12th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Kuala Lumpur, p100. 

Abdul Rahman, P.S., Doustjalali, S.R., Lim, B.K., Othman, I. and Hashim, O.H. (2002) Human cervical cancer serum proteome: detection by silver staining and enzyme-conjugated champedak lectin, 27th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p18. 

Chen, Y., Lim, B.K., Othman, I. and Hashim, O.H. (2002) Serum protein expression maps of untreated patients with ovarian carcinoma, 27th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p52. 

Doustjalali, S.R., Yusof, R., Looi, L.M., Yip, C.H., Govindasamy, G.K., Bustam, A.Z., Othman, I. and Hashim, O.H. (2002) Serum proteome maps of treated patients with breast cancer and nasopharyngeal carcinoma, 27th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p70. 

Yong, P.H., Mat Junit, S., Harun, F. and Hashim, O.H. (2002) Patients with congenital hypothyroidism demonstrate up-regulated expression of a 50-kDa serum protein, 27th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p71. 

Jalaludin, A.A., Mohamed, E., Abdul Rahman, P.S., Doustjalali, S.R. and Hashim, O.H. (2002) Profiling lectin affinity separated nasopharyngeal carcinoma serum glycoproteins, 27th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p73. 
 
2001

Shuib, A.S., Chua, C.T., Ahmad, F., Othman, I., Lim, S.B., Abdul Rahman, M., Kanthimathi, M.S. and Hashim, O.H. (2001) Champedak seed lectins: their isolation, characterisation and application in biomedical research, Proc. RMK7 IRPA Res. Sem., 1, 264-267. 

Doustjalali, S.R., Yusof, R., Looi, L.M., Yip, C.H., Othman, I. and Hashim, O.H., (2001) The human breast cancer two-dimensional serum protein expression maps generated by silver staining and lectin detection. Proc. Nat. Biotech. Sem., 13, 387-389. 

Hashim, O.H., Abdul Rahman, M. and Othman, I. (2001) The interaction of champedak seed galactose-binding lectin with human serum glycoproteins. 11th Sci. Meet. Mal. Soc. Mol. Biol Biotech., Kuala Lumpur, p22. 

Abdul Rahman, M., Karsani, S.A., Othman, I. and Hashim, O.H., (2001) Champedak seed lectin-C: the N-terminal sequence of its subunits and its application in the isolation of human serum glycoproteins. 26th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p43. 

Doust Jalali, S.R., Yusof, R., Looi, L.M., Yip, C.H., Othman, I. and Hashim, O.H., (2001) The human breast cancer serum proteome: analysis by two-dimensional gel electrophoresis and silver staining. 26th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p24. 

Doust Jalali, S.R., Yusof, R., Looi, L.M., Yip, C.H., Othman, I. and Hashim, O.H., (2001) The human breast cancer serum proteome: analysis by two-dimensional gel electrophoresis and detection by enzyme-conjugated champedak seed lectin-C. 26th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p31. 

Hashim, O.H., Ahmad, F. and Devi, S. (2001) The application of champedak seed lectin-M in the study on the acute-phase response in patients with typhoid fever. 26th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p44. 
 
2000

Hashim, O.H., Ahmad, F. and Shuib, A.A. (2000) The application of champedak seed mannose-binding lectin in the detection and isolation of selective human serum glycoproteins. 25th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p12. 

Hashim, O.H., Ahmad, F. and Shuib, A.A. (2000) The application of champedak mannose-binding lectin in the detection and isolation of selective human acute-phase proteins. 10th Mal. Assoc. Clin. Biochem. Ann Meet., Kuala Lumpur, FP1, p21. 
 
1999

Hashim, O.H. (1999) Application of lectin technology in medicine, Health Sect. Rev. Conf., UMMC Kuala Lumpur, p63. 
 
1998

Shuib, A.S., Chua, C.T. and Hashim O.H. (1998) The charge of jacalin-bound and -unbound serum IgA1. Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Kuala Lumpur, C35, 94. 

Ahmad, F, Hashim O.H. and Kanthimathi, M.S. (1998) Isolation of an N-acetyl-D-glucosamine-binding lectin from seeds of mango. Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Kuala Lumpur, A31, 60. 

Abdul Rahman, M., Hashim O.H., Othman, I., Subramaniam, R. and Hassan, J. (1998) Detection of human chorionic gonadotropin hormone by using enzyme-conjugated lectin-C. Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Kuala Lumpur, C34, p94. 

Rodgars, S.A., Hashim O.H., Yusof, R. and Junit, S.M. (1998) A suitable method for isolation of nucleic acid from freeze-dried seeds of jackfruit and champedak. Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Kuala Lumpur, C33, p94. 
 
1997

Shuib, A.S., Chua, C.T. and Hashim O.H. (1997) Characterisation of jacalin-bound and -unbound serum IgA1. Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Manila, Philippines, C 23. 

Lim S.B., Kanthimathi M.S., and Hashim O.H. (1997) Effect of champedak seed mannose-binding lectin on the proliferation of murine lymphocytes. Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Manila, Philippines, PR 68. 

Hashim, O.H. (1997) Immunoglobulin-reactive lectins from champedak seeds, University of Malaya 1997 Research Colloquium, p13. 

Shuib, A.S., Chua, C.T. and Hashim, O.H. (1997) Analyses of sera of IgA nephropathy patients using two-dimensional gel electrophoresis chromatography and jacalin-blotting. 33rd Ann. Sci. Sem. Mal. Soc. Parasit. Trop. Med., p11. 

Lim, S.B., Chua, C.T. and Hashim, O.H. (1997) Interaction of a mannose-binding Artocarpus integer seed lectin with human IgE and IgM. 33rd Ann. Sci. Sem. Mal. Soc. Parasit. Trop. Med., p11. 
 
1996

Mestecky, J., Tomana, M., Julian, B., Hashim, O.H., Jensen, J. and Radi, J. (1996) IgA nephropathy: Defect of glycosylation of IgA1 molecules. Journal of Investigative Medicine, 44(3), A321. (ISI-Cited Publication)
 
1995

Mestecky, J., Tomana, M., Hashim, O.H., Brown, R., Kulhavy, R. and Julian, B.A. (1995) Altered glycosylation pattern of IgA1 in sera of IgA nephropathy patients, FASEB Journal, 9(3): A74. (ISI-Cited Publication)
 
1994

Hashim, O.H. (1994) Defective O-linked oligosaccharide structures of IgA1 molecules as a possible etiopathogenic factor of IgA nephropathy, 12th Europ. Immunol. Meet. Barcelona, Spain, p333. 

Hashim, O.H., Gendeh, G.S., Cheong, C.N. and Nik Jaafar, M.I. (1994) Consumption of guinea-pig complement activity by jackfruit and champedak lectins, 12th Europ. Immunol. Meet. Barcelona, Spain, p139. 

Hashim, O.H. and Chong, H.A.A.H. (1994) Detection of mannose-binding lectins in crude extracts of champedak and jackfruit seeds, Proc. Mal. Biochem. Mol. Biol. Soc. Conf., 19, 230-233. 
 
1992

Hashim, O.H. and Rahim, Z.H.A. (1992) Quantitative estimation of IgA1 using Artocarpus integer lectin - a preliminary investigation. Proc. Mal. Biochem. Soc. Conf., 17, 188-191. 
 
1991

Hashim, O.H., Devadason, V. and Hassan, H. (1991) Kinetics of IgA1 protease activity from broth culture supernatant of Clostridium septicum. Proc. Mal. Biochem. Soc. Conf. 16, 100-103. 
 
1990

Rahim, Z.H.A. and Hashim, O.H. (1990) Effect of molecular size of IgA on its quantitative assay by immunonephelometry. Proc. Mal. Biochem. Soc. Conf. 15, 162-163. 

Hashim, O.H., Ng, C.L. and Nik Jaafar, M.I. (1990) Jacalin-IgA interaction: existence of two binding sites? Proc. Mal. Biochem. Soc. Conf. 15, 164-165. 
 
1989

Hashim, O.H. and Nik Jaafar, M.I. (1989) IgA binding lectin from jackfruit seeds. Proc. Mal. Biochem. Soc. Conf. 14, 210-212. 

Hashim, O.H. and Cushley, W. (1989) Affinity interaction of N-linked oligosaccharide structures of IgG2b with Concanavalin A. Proc. Mal. Biochem. Soc. Conf. 14, 217-219. 
 
1988

Hashim, O.H. and Cushley, W. (1988) Inhibition of N-linked oligosaccharide processing of IgG leads to potentiated complement fixation. Proc. Fed. Asian Oceanian Biochem. Symp. 7, 95-96. 

Wood, A., Jaques, A.M., Hashim, O.H. and Cushley, W. (1988) The role of N-linked oligosaccharides in control of expression of effector functions of a rat IgG2b monoclonal antibody. British Society for Immunology Summer Meeting, University of Strathclyde, Scotland. 38, 68-69. 
 
1986

Jones, J.A., Hashim, O.H., Wood, A. and Cushley, W. (1986) Immunochemical recognition of tyrosine phosphate and tyrosine sulphate. 6th International Congress of Immunology, Toronto, Canada. 2.73.12. 

AREAS OF RESEARCH
(Project title), (Role), (From)-(Until), (Source), (Level).

Proteomics, Cancer, Lectins, Glycosylation

Frailty Among In-patients in Geriatric Medicine, Co-Investigator, 2012-2015, Geran Penyelidikan Universiti Malaya (UMRG), National

1.proteomic explanation on the effect of Ficus deltoidea extract towards the characteristics of the reproductive organ of rats 2. Deregulated protein expression in selected cancer cell lines post-treatment with Pereskia bleo aqueous extract and fraction, Co-Investigator, 2012-2015, Postgraduate Research Grant(PPP), National

The use of acute phase reactant proteins as cancer biomarkers, Principal Investigator(PI), 2011-2015, HIR

Glycoproteomic analysis of human and mammalian milk : a lectin-based approach, Co-Investigator, 2010-2012, Fundamental Research Grant Scheme (FRGS), National

Exploring Salivary Proteins with Potential Application as Biomarkers in Clinical Diagnosis, Co-Investigator, 2009-2012, Geran Penyelidikan Universiti Malaya (UMRG), National

APPLICATION OF PROTEOMIC TECHNIQUES FOR BIOACTIVITY EVALUATION AND PROTEIN PROFILING OF FICUS DELTOIDEA, Co-Investigator, 2007-2009, MOSTI, University

Serum proteomics of patients with gestational trophoblastic diseases, Principal Investigator(PI), 2007-2009, Geran Penyelidikan Universiti Malaya (UMRG), University

Serum expression proteomics of patients with nasopharyngeal carcinoma., Principal Investigator(PI), 2007-2010, IMR/MOH Malaysia, International

Lectin-based approach in proteomic studies, Principal Investigator(PI), 2006-2008, ScienceFund, International

Application of lectin technology in medicine., Principal Investigator(PI), 2002-2006, MOSTI (IRPA), International

AWARDS AND RECOGNITIONS
(Name of Award), (Awarding Institution), (Year Awarded), (Level).

Service Loyalty Award (Twenty Years), University of Malaya, 2008, (UNIVERSITY)

National Academic Award 2007 Journal Article Publication Category., Ministry of Higher Education, Malaysia, 2008, (NATIONAL)

Excellence in Service Award for Year 2007, University of Malaya, 2008, (UNIVERSITY)

Excellent Scientist (Certificate of Merit), Ministry of Higher Education, Malaysia, 2005, (NATIONAL)

Gold Medal, 33rd International Exhibition of Inventions, Technology and New Products, Geneva, 2005, (INTERNATIONAL)

Excellence in Service Award for Year 2004, University of Malaya, 2005, (UNIVERSITY)

Silver Medal, National Science, Research and Innovation Exposition, 2004, (NATIONAL)

Gold Medal, University of Malaya Science, Research and Innovation Exposition, 2004, (UNIVERSITY)

Excellence in Service Award for Year 2000, University of Malaya, 2001, (UNIVERSITY)

Certificate of Merit for Best Presentation, University of Malaya Medical Centre (IRPA Health Sector Conference), 1999, (UNIVERSITY)

Best Stage I Lecturer Award, MedSoc, University of Malaya (voted by 1996/97 batch of MBBS students), 1997, (UNIVERSITY)

Fulbright Scholar Award, J.W. Fulbright Board of Foreign Scholarships, USA, 1993, (INTERNATIONAL)

JSPS Research Fellowship, Japan Society for the Promotion of Science, 1991, (INTERNATIONAL)

PRESENTATIONS
(Title), (Event), (Date Presented), (Organiser), (Level).
 
Pleanary/Keynote Speaker

Champedak lectins: from the humble seed to targeted proteomics., 37th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, Sime-Darby Convention Centre, KL., 18 Jul 2012, Malaysian Society for Biochemistry and Molecular Biology., (National)

Studying a study: a reviewer's perspective., INFORMM Colloquium and Scientific Wrting Workshop, 10 Oct 2009 to 10 Oct 2009, INFORMM, USM, (National)

Translating research into manuscript: points to consider., Manuscript Writing Retreat Workshop, 11 Dec 2009, USM, (National)

Lectins from the seeds of champedak: from waste to wonders., 29th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology., 01 Sep 2004, Malaysian Society for Biochemistry and Molecular Biology., (National)
 
Invited Seminar

The art and science of publishing., Publish or Perish Seminar, AMDI, USM, Kepala Batas., 18 Jun 2012, Advance Medical and Dental Institute, Universiti Sains Malaysia., (National)

Champedak seed lectins: the past, the present and the future., Faculty seminar, UMS, Kota Kinabalu, 10 Mar 2011, Faculty of Medicine, Universiti Malaysia Sabah, (University)

Studies of the champedak seed lectins: the past, the present and the future., Faculty Seminar, Faculty of Medicine, UNIMAS, Kuching, 27 May 2009, (Others)

Champedak seed lectins, Faculty Seminar, Faculty of Medicine, USIM, 16 Apr 2008, Faculty of Medicine, USIM, (University)

Champedak seed lectins: from waste to wonders., Faculty Seminar, 01 Apr 2004, Faculty of Medicine, Universiti Teknologi MARA., (National)

Immunoglobulin-reactive lectins from champedak seeds., Faculty Seminar, 01 Jun 1996, Department of Oral Biology, UM., (University)

Immunoglobulin-reactive lectins from champedak seeds., Department Seminar, 07 Mar 1995, Department of Physiology, Faculty of Medicine, University of Malaya, (University)

IgA-reactive lectins from Artocarpus seeds, Department Seminar, 11 Jul 1991, Cancer Institute, Hokkaido University School of Medicine, Sapporo, Japan, (International)

Asparagine-linked oligosaccharides of immunoglobulin A, Department Seminar, 02 Jul 1991, Department of Biochemistry, Osaka University Medical School, Osaka, Japan, (International)

IgA-reactive lectins from Artocarpus seeds, Department Seminar, 15 May 1991, Department of Biochemistry, Osaka University Medical School, Osaka, Japan, (International)

IgA-binding lectins from Artocarpus species, Department Seminar, 11 Dec 1990, Department of Microbiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, (National)

Jacalin: isolation, characterisation and application, Department Seminar, 11 Sep 1990, Department of Medical Microbiology, Faculty of Medicine, University of Malaya, (University)
 
Invited Speaker

Gel- and lectin-based proteomics studies in search for novel biomarkers for cancer., Academia Sinica - University of Malaya International Workshop., 24 Feb 2011, Academia Sinica Taiwan & University of Malaya., (International)

Proteins: the good, the bad and the ugly., HTMC Teh Tarik Club Talk., 21 Jul 2010, HTMC, (University)

Cancer biomarkers from the proteome., 35th Ann. Conf. Mal. Soc. Biochem. Mol. Biol. Conf.,, 27 Jul 2010, Malaysian Society for Biochemistry and Molecular Biology & CARIF, (National)

Writing research manuscripts for the allied health sciences., Seminar on Publishing Your Research Findings., 24 Mar 2010, Health and Translational Medicine Research Cluster, (University)

Applications of proteomics in medicine, 2DE-MS Proteomics Seminar, 23 Feb 2010, Monash University, (National)

Acute-phase protein response: can it be used as a diagnostic tool for cancer?, BIT Life Sciences 2nd Annual Protein and Peptide Conference (PepCon-2009),Seoul, Korea., 03 Apr 2009, BIT Life Sciences

Proteomics of cancer, Academy of Medicine Symposium, 07 Sep 2007, Academy of Medicine and the Ministry of Health Malaysia, (National)

Proteomics studies of cancer., 2nd International University of Malaya Research Imaging Symposium., 01 Jul 2005, Continuing Radiological Education, University of Malaya Medical Centre., (International)

Preparation and Delivery of Biochemistry lectures in the MBBS Course., 2nd Biochemical Education Workshop., 01 Jun 2005, Department of Molecular Medicine, UM., (University)

Preparation and delivery of biochemistry lectures in the MBBS Course., Workshop on the Teaching of Biochemistry in the MBBS Course, 16 May 2000, (University)

Protein chemistry and enzyme function., Training course on Industrial applications of structure-based molecular design and combinatorial chemistry., 01 Jul 1997, UM, United Nations Indust. Dev. Org. and Int. Centre for Sci. and High Techn., (International)
 
Event Organiser

Selective past proteomics studies at the University of Malaya Centre for Proteomics Research (UMCPR)., UMCPR Research Day and Proteomics Workshop, Faculty of Medicine, UM., 21 Jun 2012, UMCPR, (National)
 
Oral

Gel- and lectin-based serum proteomics profiling in search for new complementary biomarkers for cancer., National Biotechnology Conference, 26 May 2010, MOSTI, (National)

Acute-phase protein response: can it be used as a diagnostic tool for cancer?, Departmental Seminar, 15 Apr 2009, (University)

Potential role of ceruloplasmin as a novel biomarker for diagnosis and monitoring of nasopharyngeal carcinoma., 7th Federation of Asian and Oceanian Biochemist Symposium., 01 Nov 2004, International Union of Biochemistry., (International)

The interaction of champedak seed galactose-binding lectin with human serum glycoproteins., 16th Scientific Meeting of the Malaysian Society for Molecular Biology and Biotechnology., 01 May 2001, Malaysian Society for Molecular Biology and Biotechnology., (National)

Champedak seed lectins: their isolation, characterisation and application in biomedical research., RMK7 IRPA Conference, 19 Jul 2001, (University)

The application of champedak lectin in the detection and isolation of selective human acute-phase proteins., 10th scientific meeting of the Malaysian Association of Clinical Biochemists., 01 Aug 2000, Malaysian Association of Clinical Biochemists., (National)

The application of champedak seed mannose-binding lectin in the detection and isolation of human serum glycoproteins., 25th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology., 01 Oct 2000, Malaysian Society for Biochemistry and Molecular Biology., (National)

Application of lectin technology in medicine., IRPA Health Sector Review Conference, 09 Sep 1999, (University)

Immunoglobulin-reactive lectins from champedak seeds, University of Malaya Research Colloquium, 16 Jul 1997, (University)

Inhibition of N-linked oligosaccharide processing of IgG leads to potentiated complement fixation., 7th Federation of Asian and Oceanian Biochemist Symposium, 24 Nov 1988, 7th Federation of Asian and Oceanian Biochemist Symposium, (International)
 
Poster

Profiling of O-glycosylated serum proteins of patients with cancer using the gel-based proteomics approach and lectin detection., International Symposium of Glycoconjugate, 16 Jul 2007, International Glycoconjugate Society, (International)

Serum proteomic profiling of patients with endometrial and cervical carcinomas, 31st Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, 17 Aug 2006, Malaysian Society for Biochemistry and Molecular Biology, (National)

Lectin-based urinary hCG detection for confirmation of pregnancy., 12th Annual Conference of Biotechnology, India, 21 Dec 2005, (International)
 
Presenter

Selective past proteomics studies at UMCPR., APAF-UMCPR Meeting, Department of Molecular Medicine, UM., 24 Sep 2012, UMCPR, (University)

Small group teaching: how to conduct tutorial and problem solving sessions., Medical Biochemistry Teaching Workshop, Department of Molecular Medicine, UM., 30 Oct 2012, Department of Molecular Medicine, (University)

Cempedak and an immunochemist: what is the connection?, Inaugural Lecture, 05 Feb 2008, ICR, UM, (University)

MJBMB: a session with the Editor-in-Chief, 33rd Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, 28 Aug 2008, Malaysian Society for Biochemistry and Molecular Biology, (National)

Overview of basic research in biomedical sciences, Seminar and Discussion with Nobel Laureate Prof. Ahmed H. Zewail, 07 Aug 2007, University of Malaya, (University)

Champedak lectins: application in biomedical research, Department Seminar, 22 Feb 2006, Department of Molecular Medicine, (University)

SUPERVISION

 
Post Graduate Level
(Name of Degree), (Name of Candidates), (Title of Thesis), (Academic Session)

Completed

Masters Degree, Ramarao Seriramalu, Proteomic studies of patients with nasopharyngeal carcinoma, 2008/2009

Masters Degree, Shahram Golbabapour, Proteomics profiling of sera of rats chemically induced with cancer., 2008/2009

Doctoral Degree (PhD), Jessie Kala Rayappan Thomas, Proteome profiling of human saliva of cigarette smokers and non-smokers, 2008/2009

Doctoral Degree (PhD), Vanitha Mariappan, Pathogenicity of secreted extracellular proteins in Bukholderia cenocepacia Malaysian isolates using Bioinformatic tools., 2007/2008

Doctoral Degree (PhD), Puteri Shafinaz Akmar Abdul Rahman, Application of lectins in studies of protein expression in patients with cervical and endometrial cancer., 2006/2007

Doctoral Degree (PhD), Chen Yeng, Expression of proteins in sera and tissues of patients with ovarian carcinoma., 2005/2006

Masters Degree, Chai Hwa Chia, Proteome analysis and identification of immunogenic proteins of Cryptococcus neoformans, 2005/2006

Masters Degree, Yong Phaik Har, Plasma protein expression profiles and PAX8 gene mutation(s) screening of patients with congenital hypothyroidism., 2003/2004

Doctoral Degree (PhD), Saeid Reza Doust Jalali, Proteins expression in patients with malignant and benign breast tumours., 2003/2004

Masters Degree, Emida Mohamed, Application of mannose-binding champedak lectin in the isolation and detection of serum glycoproteins., 2002/2003

Masters Degree, Anil Azura Jalaludin, Application of galactose-binding champedak lectin in the isolation and detection of serum glycoproteins., 2002/2003

Doctoral Degree (PhD), Norhaniza Aminudin, Euricoma longifolia aqueous extract-bioactive compound and its effects toward hormone production and spermatogenesis., 2002/2003

Masters Degree, Faizah Ahmad, Characterisation and application of mannose-binding lectin from the seeds of champedak., 2000/2001

Masters Degree, Mariati Abdul Rahman, Characterisation and application of galactose-binding lectin from the seeds of champedak., 2000/2001

Masters Degree, Adawiyah Suriza Shuib, The application of lectins in the study of serum IgA1 from IgA nephropathy patients, 1997/1998

Masters Degree, Lim Sing Bin, Mannose-binding lectin from seeds of Artocarpus integer, 1996/1997

Masters Degree, Gurmil Singh Gendeh, IgA binding lectins from Artocarpus integer, 1990/1991

Ongoing

Doctoral Degree (PhD), Emida Mohamed, Proteomics studies of patients with gestational trophoblastic disease., 2008/2009

Doctoral Degree (PhD), Jameel Rabee Al-Obaidi, Interaction between E. guineensis and G. boninense causing basal stem rot, 2007/2008

Doctoral Degree (PhD), Kumutha Malar Vellasamy, Studies of Burkholderia pseudomallei and B. thailandensis, 2007/2008

INTELLECTUAL PROPERTY RIGHTS
(Product Name), (Type), (Reference), (Year), (Level).

A Lectin-Based Urinary Human Chorionic Gonadotropin Binding Detection Kit For Confirmation of Pregnancy , Patent, UM.AC/UPTK/628/15

Lectin-based pregnancy test kit (method for detecting hCG hormone and test kit thereof), Patent, PI20041268., 2004, (National)

A method for detecting the 35kDa O-glycosylated inter-alpha-trypsin inhibitor heavy chain H4 fragments., Patent, PI 2008 4944, 2008, (National)

EXPERT LINKAGES
(Linkages Description), (Organisation), (Year of Involvement), (Duration), (Level).

Project on proteomic studies of serum from patients with nasopharyngeal carcinoma., Molecular Pathology Unit, Cancer Research Centre, Institute for Medical Research, Malaysia., 2007, 36, (National)

Project on crystallisation of champedak seed lectins, Glasgow Biomedical Research Centre, University of Glasgow, 2008, 36, (International)

EXPERT/TECHNICAL CONTRIBUTIONS
(Activity), (Organisation), (Role), (From)-(Until), (Level).

External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, MARA University of Teknology, Expert Advisor, 2004, (University)

Consultant on lectin-based projects, Forest Research Institute Malaysia, Cargill Malaysia Sdn. Bhd. and Ema Consultancy Sdn. Bhd., Consultant , 2006, (National)

Panel evaluator (Technical) for monitoring and evaluation of R&D Science Fund Research Projects (Biotechnology), Ministry of Science, Technology and Innovation, Malaysia., Technical Advisor, 2007-2008, (National)

External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, Islamic Science University of Malaysia, Expert Advisor, 2008, (National)

Accreditation Panel Member (Medical Biochemistry), Malaysian Qualificaions Agency (MQA), Expert Advisor, 2008-2012, (National)

External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, Melaka Manipal Medical College, Manipal, India, Expert Advisor, 2008, 2009, 2010, (International)

External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, International Medical University, Expert Advisor, 2008, 2010, (National)

External Examiner of the Biochemistry programme of the Bachelor of Dental Surgery (BDS) Course, MARA University of Technology, Expert Advisor, 2009, (National)

External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, Universiti Malaysia Sarawak, Expert Advisor, 2009, (National)

External Academic Advisor, School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Expert Advisor, 2009, (National)

External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, Universiti Kebangsaan Malaysia, Expert Advisor, 2009, (National)

External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, Universiti Malaysia Sabah, Expert Advisor, 2011-2012, (National)

External Examiner of the Biochemistry programme of the Bachelor of Dental Surgery (BDS) Course, International Islamic University Malaysia,, Expert Advisor, 2011-2012, (National)

External Examiner for the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course of CUCMS, Cyberjaya University College of Medical Sciences, Expert Advisor, 2012-2012, (National)

EVALUATION ACTIVITIES
(Description), (Evaluation Activity),(Year).

Reviewer of scientific manuscripts for peer-reviewed international journals: Electrophoresis, PLoS ONE, Journal of Cancer Research and Clinical Oncology, International Journal of Cancer, Proteomics, Cancer Cell International, and Bioorganic & Medicinal Chemistry Letters., Article , 

Mechanisms of action of vitamin E (-tocopherol dan -tocotrienol) and hydrogen peroxide on liver cancer cells, HepG2 (PhD, UKM 2007)., Thesis , 

Identification of immunogenic proteins extracted from sera from individuals infected by Plasmodium knowlesi (MSc, USM, 2012)., Thesis ,  (2012)

Characterization of Entamoeba histolica antigens in pus aspirate and serum of patients with amoebic liver abscess (PhD, USM, 2012), Thesis ,  (2012)

In vivo study of the effects of angiogenic supression and protein kinase C inhibition on breast cancer (MSc, USM, 2012)., Thesis ,  (2012)

MicroRNAs in diabetes mellitus and metabolic syndrome (PhD, NUS, 2012)., Thesis ,  (2012)

Development of a proteome map and identification of potential protein markers for gestational diabetes mellitus (MSc, UPM, 2012)., Thesis ,  (2012)

Antiproliferative effects and safety evaluation of Euricoma longifolia jack (Tongkat Ali) extracts (MSc, UKM 2003)., Thesis , 

Induction of cytochrome C mediated apoptosis by goniothalamine on human breast cancer cells MCF-7 (MSc, UKM 2004)., Thesis , 

Effects of palm vitamin E suplementation on the oxidative status in the formation of steroid-induced cataract (MSc, UKM 2004)., Thesis , 

Studies on the hyaluronidase enzyme purified from the venom of Chinese red scorpion Buthus martensi Karsch (PhD, National University of Singapore, 2009)., Thesis , 

Detection and Characterization of Circulating Toxoplasma gondii Antigens and Host Specific Proteins in Toxoplasmosis via Serum Proteomic Approach (PhD, USM, 2010)., Thesis , 

Identification of putative target and ligand molecules of tocotrienols in MCF-7 human breast cancer cells (MSc, IMU 2010), Thesis ,  (2010)

In vitro studies of zerumbone, a natural plant product with chemotherapeutic potential for ovarian and cervical cancers (MSc,UPM 2005)., Thesis , 

Euricomanone demonstrates anti-proliferative activity through apoptosis in MCF-7 cells (PhD, UKM 2005)., Thesis , 

Generation and characterisation of anti thymidine kinase 1 antibody as a potential tumour marker (MSc, UKM 2006)., Thesis , 

Monitoring and Evaluation of R&D Science Fund Research Projects (Biotechnology), MOSTI., Project , 

External evaluator (Health Sector) for Research and Innovation Expositions, Universiti Kebangsaan Malaysia (2004 & 2005)., Project , 

Malaysian Journal of Biochemistry and Molecular Biology, 2006-2009., Article In Journal , 

Promotion/intake exercise of Professors and/or Associate Professors for Universiti Kebangsaan Malaysia, Universiti Putra Malaysia, Universiti Sains Malaysia, Universiti Sains Islam Malaysia, International Medical University and Monash University Sunway Campus., External Assessor , 

Panel Evaluator of research proposals and panel interviewer for National Science Fellowship (2007)., Candidate Evaluation , 

Promotion/Intake Exercise, UKM, UPM, USM, USIM and IMU., Staff Achievements , 

CONTRIBUTION TO SOCIETY
(Contribution To Society), (Level), (Start Date), (End Date).

Editorial Board member, Biomarker Research., (International), 16-Aug-12 until 15-Aug-17

National Academic Award 2011 Selection Committee, (National), 01-Jan-12 until 31-Dec-12

National Academic Award 2010 Selection Committee, (National), 01-Jan-11 until 31-Dec-11

Expert Panel for Evaluation of Funding for Research, Development and Commercialisation, appointed by MOSTI., (National), 14-Jul-10 until 13-Jul-12

Road-show for the National Academic Award 2009 - Journal Article Publication Category, PICC., (National), 29-Apr-10

Member, Editorial Board, Journal of the University of Malaya Medical Centre (JUMMEC)., (University), 01-Feb-10 until 31-Jan-13

National Academic Award 2009 Selection Committee, (National), 01-Jan-10

Panel member of the MBMMBI Meeting on feedback on strengthening of the teaching of English, Ministry of Education (2009)., (Country), 03-Aug-09

National Academic Award 2008 Selection Committee, (National), 10-Feb-09

Committee Member, National Strategic Sector Advisory Committee (Biotechnology), appointed by MOHE., (National), 15-Aug-07 until 14-Jul-09

Editor-in-Chief of the Malaysian Journal of Biochemistry and Molecular Biology (2006 2009)., (National), 02-Jan-06 until 31-Dec-09

Chairman of Scientific Sub-committee of the 28th Malaysian Society for Biochemistry and Molecular Biology Annual Conference (2003)., (National), 18-Sep-03

Chairman of Scientific Sub-committee of the 27th Malaysian Society for Biochemistry and Molecular Biology Annual Conference (2002)., (National), 20-Sep-02

Organising Committee Member of the 26th Malaysian Society for Biochemistry and Molecular Biology Annual Conference (2001)., (National), 20-Sep-01

Member, Editorial Board of the Malaysian Journal of Biochemistry and Molecular Biology, (National), 03-Jan-00 until 30-Dec-05

Secretary, 14th Malaysian Biochemical Society Conference. , (National), 17-Aug-89

Organising Committee Member, Education and Teaching of Biochemistry Workshop, sponsored by International Union of Biochemistry., (Local), 19-Aug-88

BIOGRAPHY

Professor Onn Hashim obtained his PhD in immunochemistry from the University of Glasgow, United Kingdom, in December 1987. He joined the University of Malaya in January 1988 and is currently a Professor at the Department of Molecular Medicine since February 2003. During his career, Professor Onn had spent short sabbaticals at the University of Alabama at Birmingham, USA, under the sponsorship of the American Fulbright Scholar Programme, and the University of Osaka Medical School, Japan, through the JSPS Exchange Fellowship. Professor Onn is recipient of the National Academic Award 2007 (Journal Article Publication Category). He had acted as External Examiner of the MBBS/MD (Biochemistry) programmes at seven medical schools and sat on numerous expert advisory and evaluation committees at the university and national levels. Professor Onn had performed considerable studies on the champedak seed lectins and their applications. His current research interest is in proteomics, particularly in the use of the gel-based and lectin approaches in the search for novel complementary biomarkers in serum, urine and saliva samples from patients with cancer. He had identified serum glycoproteins that are potentially useful in cancer diagnosis and also proposed that the acute-phase response pattern may be used as fingerprints for diagnosis of cancer. Professor Onn was Editor-in-Chief of the Malaysian Journal of Biochemistry and Molecular Biology from 2006 to 2009. He is currently Head of the Department of Molecular Medicine as well as the University of Malaya Centre for Proteomics Research.